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10.33549/physiolres.931235 http://scihub22266oqcxt.onion/10.33549/physiolres.931235 18052684!ä!18052684 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Physiol+Res 2008 ; 57 (6): 839-846 Nephropedia Template TP {{tp|p=18052684|t=2008. Importance of timing of magnesium administration in the isolated ischemic-reperfused rat heart: role of K(ATP) channels |pdf=|usr=}}{{18052684}} gab.com Text Importance of timing of magnesium administration in the isolated ischemic-reperfused rat heart: role of K(ATP) channels JO: Physiol Res http://www.kidney.de/pget.php?&tw=1&pmid=18052684 #FOAvip There is a growing interest for the beneficial effect of magnesium (Mg) in cardiovascular disorders. A number of cardiovascular disorders including myocardial infarction, arrhythmias and congestive heart failure have been associated with low extra- cellular or intracellular concentrations of Mg. The efficiency of the preconditioning effect of Mg on cardiac function and infarct size in the globally ischemic-reperfused isolated rat heart was studied together with the role of ATP-sensitive potassium (K(ATP)) channels in protection induced by Mg. Rat hearts were Langendorff perfused, subjected to 30 min of global ischemia and 90 min of reperfusion, including treatment groups which focused on different times of Mg (8 mmol/l) use. Infarct size was measured by triphenyltetrazolium chloride (TTC) method. The left ventricular function was assessed by left ventricular developed pressure (LVDP), heart rate (HR) and coronary flow (CF). The administration of Mg before ischemia had an anti-infarct effect in rat hearts and improved cardiac function. The protective effects of magnesium was abolished by the blocking of K(ATP) channels and suggests that K-ATP channel has an important role in the heart protection effect of Mg as a preconditioning agent. Twit Text FOAVip Importance of timing of magnesium administration in the isolated ischemic-reperfused rat heart: role of K(ATP) channels ????Physiol Res http://www.kidney.de/pget.php?&tw=1&pmid=18052684 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=18052684 #FOAvip English Wikipedia <ref>{{Cite pmid|18052684}}</ref> Importance of timing of magnesium administration in the isolated ischemic-reperfused rat heart: role of K(ATP) channels #MMPMID18052684 Bazargan M; Faghihi M; Chitsaz M Physiol Res 2008[]; 57 (6): 839-846 PMID18052684show ga There is a growing interest for the beneficial effect of magnesium (Mg) in cardiovascular disorders. A number of cardiovascular disorders including myocardial infarction, arrhythmias and congestive heart failure have been associated with low extra- cellular or intracellular concentrations of Mg. The efficiency of the preconditioning effect of Mg on cardiac function and infarct size in the globally ischemic-reperfused isolated rat heart was studied together with the role of ATP-sensitive potassium (K(ATP)) channels in protection induced by Mg. Rat hearts were Langendorff perfused, subjected to 30 min of global ischemia and 90 min of reperfusion, including treatment groups which focused on different times of Mg (8 mmol/l) use. Infarct size was measured by triphenyltetrazolium chloride (TTC) method. The left ventricular function was assessed by left ventricular developed pressure (LVDP), heart rate (HR) and coronary flow (CF). The administration of Mg before ischemia had an anti-infarct effect in rat hearts and improved cardiac function. The protective effects of magnesium was abolished by the blocking of K(ATP) channels and suggests that K-ATP channel has an important role in the heart protection effect of Mg as a preconditioning agent. |Animals[MESH] |Cardiotonic Agents/*administration & dosage[MESH] |Coronary Circulation/drug effects[MESH] |Diazoxide/pharmacology[MESH] |Drug Administration Schedule[MESH] |Glyburide/pharmacology[MESH] |Heart Rate/drug effects[MESH] |In Vitro Techniques[MESH] |KATP Channels/*drug effects/metabolism[MESH] |Magnesium Compounds/*administration & dosage[MESH] |Male[MESH] |Myocardial Infarction/metabolism/physiopathology/*prevention & control[MESH] |Myocardial Reperfusion Injury/metabolism/physiopathology/*prevention & control[MESH] |Myocardium/*metabolism/pathology[MESH] |Perfusion[MESH] |Potassium Channel Blockers/pharmacology[MESH] |Rats[MESH] |Rats, Sprague-Dawley[MESH] |Ventricular Function, Left/drug effects[MESH]Importance of timing of magnesium administration in the isolated isch(epmc).pdf DeepDyve Pubget Overpricing