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10.1016/j.jemermed.2007.03.053 http://scihub22266oqcxt.onion/10.1016/j.jemermed.2007.03.053 18022786!ä!18022786 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Emerg+Med 2008 ; 34 (3): 287-90 Nephropedia Template TP {{tp|p=18022786|t=2008. Chronic methadone therapy complicated by torsades de pointes: a case report |pdf=|usr=}}{{18022786}} gab.com Text Chronic methadone therapy complicated by torsades de pointes: a case report JO: J Emerg Med http://www.kidney.de/pget.php?&tw=1&pmid=18022786 #FOAvip Methadone is commonly used by patients presenting to the Emergency Department (ED). The common, acute side effects of central nervous system depression and respiratory depression are easily recognizable by treating physicians as attributable to methadone; however, the cardiac toxicity of chronic methadone use recently has only been recognized. Both chronic use of large doses and a recent increase in the daily dose of methadone have been associated with QT prolongation and subsequent development of torsades de pointes. We describe the case of a 40-year-old woman whose methadone dose recently had been increased to 135 mg per day. She then presented to the ED with symptomatic torsades de pointes. She was stabilized in the ED by cardioversion and infusions of magnesium sulfate and lidocaine. The markedly prolonged corrected QT interval significantly shortened after discontinuing methadone. Inpatient cardiology evaluation found no other cause for the dysrhythmia. She was definitively treated with reduction of the daily methadone dose and an implanted cardioverter-defibrillator. Twit Text FOAVip Chronic methadone therapy complicated by torsades de pointes: a case report ????J Emerg Med http://www.kidney.de/pget.php?&tw=1&pmid=18022786 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=18022786 #FOAvip English Wikipedia <ref>{{Cite pmid|18022786}}</ref> Chronic methadone therapy complicated by torsades de pointes: a case report #MMPMID18022786 Pimentel L; Mayo D J Emerg Med 2008[Apr]; 34 (3): 287-90 PMID18022786show ga Methadone is commonly used by patients presenting to the Emergency Department (ED). The common, acute side effects of central nervous system depression and respiratory depression are easily recognizable by treating physicians as attributable to methadone; however, the cardiac toxicity of chronic methadone use recently has only been recognized. Both chronic use of large doses and a recent increase in the daily dose of methadone have been associated with QT prolongation and subsequent development of torsades de pointes. We describe the case of a 40-year-old woman whose methadone dose recently had been increased to 135 mg per day. She then presented to the ED with symptomatic torsades de pointes. She was stabilized in the ED by cardioversion and infusions of magnesium sulfate and lidocaine. The markedly prolonged corrected QT interval significantly shortened after discontinuing methadone. Inpatient cardiology evaluation found no other cause for the dysrhythmia. She was definitively treated with reduction of the daily methadone dose and an implanted cardioverter-defibrillator. |*Electrocardiography[MESH] |Adult[MESH] |Defibrillators, Implantable[MESH] |Female[MESH] |Heroin Dependence/*rehabilitation[MESH] |Humans[MESH] |Methadone/administration & dosage/*adverse effects[MESH] |Narcotics/administration & dosage/*adverse effects[MESH]Chronic methadone therapy complicated by torsades de pointes: a case r(epmc).pdf DeepDyve Pubget Overpricing