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10.1007/BF02977637 http://scihub22266oqcxt.onion/10.1007/BF02977637 17679553!ä!17679553 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Arch+Pharm+Res 2007 ; 30 (6): 743-9 Nephropedia Template TP {{tp|p=17679553|t=2007. Effects of supplementation with higher levels of manganese and magnesium on immune function |pdf=|usr=}}{{17679553}} gab.com Text Effects of supplementation with higher levels of manganese and magnesium on immune function JO: Arch Pharm Res http://www.kidney.de/pget.php?&tw=1&pmid=17679553 #FOAvip The magnesium (Mg) and manganese (Mn) were evaluated for its effectiveness as an immunomodulator in rats. The treatments were as follows: Group 1, AIN-93M diet (0.05% Mg, 0.001% Mn); Group 2, high-dose Mg (0.1% Mg, 0.001% Mn); and Group 3, high dose Mn (0.05% Mg, 0.01% Mn) (n-12/group). After 12 weeks of supplementation, rats were sacrificed to assess the effect on a range of innate responses (tumoricidal activity, oxidative burst and nitric oxide) and the mitogen-stimulated lymphoproliferative response. Immune function was significantly affected in both the high dose Mg and the Mn group. Lymphocyte proliferative responses and NK cell activity were measured in pooled spleen from each group. The mitogen response of lymphocytes to LPS in the spleen was significantly reduced in high dose Mg-treated groups, whereas the response to ConA was not affected in both high dose minerals-treated groups. The reactive oxygen species level of macrophages was decreased in both groups. These effects were more pronounced in high dose Mg-treated group. Nitric oxide production was also decreased in high dose minerals-treated group. In addition, tumoricidal activities of splenic NK cell and peritoneal macrophage in mineral exposed rats were significantly increased. Moreover, percent death of macrophage was reduced in two groups receiving high dose mineral supplements. Taken together, the present data suggest that high dose trace min erals exert a differential effect on the function of immune cells. Twit Text FOAVip Effects of supplementation with higher levels of manganese and magnesium on immune function ????Arch Pharm Res http://www.kidney.de/pget.php?&tw=1&pmid=17679553 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=17679553 #FOAvip English Wikipedia <ref>{{Cite pmid|17679553}}</ref> Effects of supplementation with higher levels of manganese and magnesium on immune function #MMPMID17679553 Son EW; Lee SR; Choi HS; Koo HJ; Huh JE; Kim MH; Pyo S Arch Pharm Res 2007[Jun]; 30 (6): 743-9 PMID17679553show ga The magnesium (Mg) and manganese (Mn) were evaluated for its effectiveness as an immunomodulator in rats. The treatments were as follows: Group 1, AIN-93M diet (0.05% Mg, 0.001% Mn); Group 2, high-dose Mg (0.1% Mg, 0.001% Mn); and Group 3, high dose Mn (0.05% Mg, 0.01% Mn) (n-12/group). After 12 weeks of supplementation, rats were sacrificed to assess the effect on a range of innate responses (tumoricidal activity, oxidative burst and nitric oxide) and the mitogen-stimulated lymphoproliferative response. Immune function was significantly affected in both the high dose Mg and the Mn group. Lymphocyte proliferative responses and NK cell activity were measured in pooled spleen from each group. The mitogen response of lymphocytes to LPS in the spleen was significantly reduced in high dose Mg-treated groups, whereas the response to ConA was not affected in both high dose minerals-treated groups. The reactive oxygen species level of macrophages was decreased in both groups. These effects were more pronounced in high dose Mg-treated group. Nitric oxide production was also decreased in high dose minerals-treated group. In addition, tumoricidal activities of splenic NK cell and peritoneal macrophage in mineral exposed rats were significantly increased. Moreover, percent death of macrophage was reduced in two groups receiving high dose mineral supplements. Taken together, the present data suggest that high dose trace min erals exert a differential effect on the function of immune cells. |*Dietary Supplements[MESH] |Calcium[MESH] |Cell Proliferation/drug effects[MESH] |Coloring Agents[MESH] |Immunity/*drug effects[MESH] |Immunologic Factors/pharmacology[MESH] |Indicators and Reagents[MESH] |Killer Cells, Natural/drug effects[MESH] |Macrophages/drug effects/immunology[MESH] |Magnesium/*pharmacology[MESH] |Manganese/*pharmacology[MESH] |Mitogens/pharmacology[MESH] |Nitric Oxide/metabolism[MESH] |Propidium/pharmacology[MESH] |Reactive Oxygen Species/metabolism[MESH] |T-Lymphocytes, Cytotoxic/drug effects[MESH]Effects of supplementation with higher levels of manganese and magnesi(epmc).pdf DeepDyve Pubget Overpricing