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Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Int+J+Vitam+Nutr+Res 2006 ; 76 (3): 111-6 Nephropedia Template TP
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Dietary calcium supplementation suppresses bone formation in magnesium-deficient rats #MMPMID17048189
Matsuzaki H; Miwa M
Int J Vitam Nutr Res 2006[May]; 76 (3): 111-6 PMID17048189show ga
The purpose of this study was to clarify the effects of dietary calcium (Ca) supplementation on bone metabolism of magnesium (Mg)-deficient rats. Male Wistar rats were randomized by weight into three groups, and fed a control diet (control group), a Mg-deficient diet (Mg- group) or a Mg-deficient diet having twice the control Ca concentrations (Mg-2Ca group) for 14 days. Trabecular bone volume was significantly lower in the Mg- and Mg-2Ca groups than in the control group. Trabecular number was also significantly lower in the Mg- and Mg-2Ca groups than in the control group. Mineralizing bone surface, mineral apposition rate (MAR), and surface referent bone formation rate (BFR/BS) were significantly lower in the Mg- and Mg-2Ca groups than in the control group. Furthermore, MAR and BFR/BS were significantly lower in the Mg-2Ca group than in the Mg- group. These results suggest that dietary Ca supplementation suppresses bone formation in Mg-deficient rats.
|*Dietary Supplements[MESH]
|Analysis of Variance[MESH]
|Animals[MESH]
|Body Weight/drug effects[MESH]
|Bone Density Conservation Agents/*administration & dosage[MESH]
Int+J+Vitam+Nutr+Res 2006 ; 76 (3): 111-6
