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Deprecated: Implicit conversion from float 247.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Rheumatol+Int 2007 ; 27 (4): 411-4 Nephropedia Template TP
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A case of pure red cell aplasia and systemic lupus erythematosus caused by human parvovirus B19 infection #MMPMID17028860
Ideguchi H; Ohno S; Ishigatsubo Y
Rheumatol Int 2007[Feb]; 27 (4): 411-4 PMID17028860show ga
Human parvovirus B19 (B19) rarely induces pure red cell aplasia (PRCA) in healthy hosts. Meanwhile B19 infection is often clinically similar to systemic lupus erythematosus (SLE), and several cases have been reported wherein B19 actually stimulated SLE exacerbation in an immunocompetent subject. An 82-year-old healthy woman was diagnosed to have complicated with B19 infection and PRCA. Four weeks later, she had high fever, polyarthritis, and oral ulcers, additionally diagnosed with SLE, and subsequently, 15 mg of prednisone was started. This is the first case wherein B19 infection caused both PRCA and SLE in a healthy patient as far as our investigations are concerned.