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10.1242/dev.02595 http://scihub22266oqcxt.onion/10.1242/dev.02595 17021045!ä!17021045 Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=17021045&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\17021045.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Development 2006 ; 133 (21): 4131-43 Nephropedia Template TP {{tp|p=17021045|t=2006. The roles of cilia in developmental disorders and disease |pdf=|usr=}}{{17021045}} gab.com Text The roles of cilia in developmental disorders and disease JO: Development http://www.kidney.de/pget.php?&tw=1&pmid=17021045 #FOAvip Cilia are highly conserved organelles that have diverse motility and sensory functions. Recent discoveries have revealed that cilia also have crucial roles in cell signaling pathways and in maintaining cellular homeostasis. As such, defects in cilia formation or function have profound effects on the development of body pattern and the physiology of multiple organ systems. By categorizing syndromes that are due to cilia dysfunction in humans and from studies in vertebrate model organisms, molecular pathways that intersect with cilia formation and function have come to light. Here, we summarize an emerging view that in order to understand some complex developmental pathways and disease etiologies, one must consider the molecular functions performed by cilia. Twit Text FOAVip The roles of cilia in developmental disorders and disease ????Development http://www.kidney.de/pget.php?&tw=1&pmid=17021045 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=17021045 #FOAvip English Wikipedia <ref>{{Cite pmid|17021045}}</ref> The roles of cilia in developmental disorders and disease #MMPMID17021045 Bisgrove BW; Yost HJ Development 2006[Nov]; 133 (21): 4131-43 PMID17021045show ga Cilia are highly conserved organelles that have diverse motility and sensory functions. Recent discoveries have revealed that cilia also have crucial roles in cell signaling pathways and in maintaining cellular homeostasis. As such, defects in cilia formation or function have profound effects on the development of body pattern and the physiology of multiple organ systems. By categorizing syndromes that are due to cilia dysfunction in humans and from studies in vertebrate model organisms, molecular pathways that intersect with cilia formation and function have come to light. Here, we summarize an emerging view that in order to understand some complex developmental pathways and disease etiologies, one must consider the molecular functions performed by cilia. |*Human Development[MESH] |Animals[MESH] |Bardet-Biedl Syndrome/metabolism/physiopathology[MESH] |Cell Polarity[MESH] |Cilia/*physiology/ultrastructure[MESH] |Ciliary Motility Disorders/*metabolism/physiopathology[MESH] |Flagella/metabolism[MESH] |Homeostasis[MESH] |Humans[MESH] |Mechanotransduction, Cellular/physiology[MESH] |Microtubules/metabolism[MESH] |Polycystic Kidney Diseases/metabolism/physiopathology[MESH] |Signal Transduction/*physiology[MESH]The roles of cilia in developmental disorders and disease (epmc).pdf DeepDyve Pubget Overpricing