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10.4161/cc.5.13.2928 http://scihub22266oqcxt.onion/10.4161/cc.5.13.2928 16855389!ä!16855389 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cell+Cycle 2006 ; 5 (13): 1426-30 Nephropedia Template TP {{tp|p=16855389|t=2006. Control of murine kidney development by sonic hedgehog and its GLI effectors |pdf=|usr=}}{{16855389}} gab.com Text Control of murine kidney development by sonic hedgehog and its GLI effectors JO: Cell Cycle http://www.kidney.de/pget.php?&tw=1&pmid=16855389 #FOAvip Sonic hedgehog (SHH) controls cell differentiation and morphogenesis in many tissues and species. The mammalian kidney is a paradigm for studying epithelial-mesenchymal interactions and growth factor signaling during embryogenesis. Here, we review our recent findings demonstrating that SHH is required for normal murine kidney development. During renal morphogenesis, SHH controls a hierarchy of genes including renal patterning genes, cell cycle modulators, and GLI family members. Our investigation of GLI protein processing and binding of GLI activators and repressor to SHH target genes provide insight into the molecular mechanisms by which SHH and its GLI family of effectors control renal embryogenesis. Further, we highlight the roles of BMP, WNT and FGF signaling during renal development and discuss possible interactions of these pathways with SHH signaling. Twit Text FOAVip Control of murine kidney development by sonic hedgehog and its GLI effectors ????Cell Cycle http://www.kidney.de/pget.php?&tw=1&pmid=16855389 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=16855389 #FOAvip English Wikipedia <ref>{{Cite pmid|16855389}}</ref> Control of murine kidney development by sonic hedgehog and its GLI effectors #MMPMID16855389 Gill PS; Rosenblum ND Cell Cycle 2006[Jul]; 5 (13): 1426-30 PMID16855389show ga Sonic hedgehog (SHH) controls cell differentiation and morphogenesis in many tissues and species. The mammalian kidney is a paradigm for studying epithelial-mesenchymal interactions and growth factor signaling during embryogenesis. Here, we review our recent findings demonstrating that SHH is required for normal murine kidney development. During renal morphogenesis, SHH controls a hierarchy of genes including renal patterning genes, cell cycle modulators, and GLI family members. Our investigation of GLI protein processing and binding of GLI activators and repressor to SHH target genes provide insight into the molecular mechanisms by which SHH and its GLI family of effectors control renal embryogenesis. Further, we highlight the roles of BMP, WNT and FGF signaling during renal development and discuss possible interactions of these pathways with SHH signaling. |Animals[MESH] |Gene Expression Regulation, Developmental[MESH] |Hedgehog Proteins/genetics/*metabolism[MESH] |Humans[MESH] |Kidney/*embryology/*metabolism[MESH] |Kruppel-Like Transcription Factors/genetics/*metabolism[MESH] |Mice[MESH] |Protein Binding[MESH] |Signal Transduction[MESH]Control of murine kidney development by sonic hedgehog and its GLI eff(epmc).pdf DeepDyve Pubget Overpricing