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10.1517/13543784.15.2.89 http://scihub22266oqcxt.onion/10.1517/13543784.15.2.89 16433589!7103689!16433589     free     free     free       Expert+Opin+Investig+Drugs 2006 ; 15 (2): 89-97 Nephropedia Template TP {{tp|p=16433589|t=2006. Antiviral applications of RNAi for coronavirus |pdf=|usr=}}{{16433589}} gab.com Text Antiviral applications of RNAi for coronavirus JO: Expert Opin Investig Drugs http://www.kidney.de/pget.php?&tw=1&pmid=16433589 #FOAvip Until the appearance of severe acute respiratory syndrome (SARS), caused by the SARS coronavirus (SARS-CoV) in early 2003, coronavirus infection was not considered to be serious enough to be controlled by either vaccination or specific antiviral therapy. It is now believed that the availability of antiviral drugs effective against SARS-CoV will be crucial for the control of future SARS outbreaks. Recently, RNA interference has been successfully used as a more specific and efficient method for gene silencing. RNA interference induced by small interfering RNA can inhibit the expression of viral antigens and so provides a new approach to the therapy of pathogenic viruses. This review provides an overview of current information on coronavirus and the application of small interfering RNA in viral therapeutics, with particular reference to SARS-CoV. Twit Text FOAVip Antiviral applications of RNAi for coronavirus ????Expert Opin Investig Drugs http://www.kidney.de/pget.php?&tw=1&pmid=16433589 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=16433589 #FOAvip English Wikipedia <ref>{{Cite pmid|16433589}}</ref> Antiviral applications of RNAi for coronavirus #MMPMID16433589 Wu CJ; Chan YL Expert Opin Investig Drugs 2006[Feb]; 15 (2): 89-97 PMID16433589show ga Until the appearance of severe acute respiratory syndrome (SARS), caused by the SARS coronavirus (SARS-CoV) in early 2003, coronavirus infection was not considered to be serious enough to be controlled by either vaccination or specific antiviral therapy. It is now believed that the availability of antiviral drugs effective against SARS-CoV will be crucial for the control of future SARS outbreaks. Recently, RNA interference has been successfully used as a more specific and efficient method for gene silencing. RNA interference induced by small interfering RNA can inhibit the expression of viral antigens and so provides a new approach to the therapy of pathogenic viruses. This review provides an overview of current information on coronavirus and the application of small interfering RNA in viral therapeutics, with particular reference to SARS-CoV. |Animals[MESH] |Antiviral Agents/pharmacology/*therapeutic use[MESH] |Coronavirus Infections/*drug therapy/genetics/metabolism[MESH] |Coronavirus/*drug effects/physiology[MESH] |Humans[MESH]Antiviral applications of RNAi for coronavirus (epmc).pdf DeepDyve Pubget Overpricing