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10.1002/cbic.200500321 http://scihub22266oqcxt.onion/10.1002/cbic.200500321 16397876!7161998!16397876     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=16397876&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215       Chembiochem 2006 ; 7 (1): 165-73 Nephropedia Template TP {{tp|p=16397876|t=2006. Novel five-membered iminocyclitol derivatives as selective and potent glycosidase inhibitors: new structures for antivirals and osteoarthritis |pdf=|usr=}}{{16397876}} gab.com Text Novel five-membered iminocyclitol derivatives as selective and potent glycosidase inhibitors: new structures for antivirals and osteoarthritis JO: Chembiochem http://www.kidney.de/pget.php?&tw=1&pmid=16397876 #FOAvip A novel 5-membered iminocyclitol derivative was found to be a potent and selective inhibitor of the glycoprotein-processing alpha-glucosidase with a Ki value of 53 nM. This compound was further derivatized to antiviral agents against Japanese encephalitis virus, dengue virus serotype 2 (DEN-2), human SARS coronavirus, and human beta-hexosaminidase (Ki = 2.6 nM), a new target for the development of osteoarthritis therapeutics. Twit Text FOAVip Novel five-membered iminocyclitol derivatives as selective and potent glycosidase inhibitors: new structures for antivirals and osteoarthritis ????Chembiochem http://www.kidney.de/pget.php?&tw=1&pmid=16397876 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=16397876 #FOAvip English Wikipedia <ref>{{Cite pmid|16397876}}</ref> Novel five-membered iminocyclitol derivatives as selective and potent glycosidase inhibitors: new structures for antivirals and osteoarthritis #MMPMID16397876 Liang PH; Cheng WC; Lee YL; Yu HP; Wu YT; Lin YL; Wong CH Chembiochem 2006[Jan]; 7 (1): 165-73 PMID16397876show ga A novel 5-membered iminocyclitol derivative was found to be a potent and selective inhibitor of the glycoprotein-processing alpha-glucosidase with a Ki value of 53 nM. This compound was further derivatized to antiviral agents against Japanese encephalitis virus, dengue virus serotype 2 (DEN-2), human SARS coronavirus, and human beta-hexosaminidase (Ki = 2.6 nM), a new target for the development of osteoarthritis therapeutics. |*Imino Pyranoses/chemical synthesis/chemistry/pharmacology[MESH] |Animals[MESH] |Antiviral Agents/chemical synthesis/chemistry/*pharmacology[MESH] |Cell Line[MESH] |Cell Proliferation/drug effects[MESH] |Combinatorial Chemistry Techniques[MESH] |Dengue Virus/drug effects[MESH] |Encephalitis Virus, Japanese/drug effects[MESH] |Enzyme Inhibitors/chemical synthesis/chemistry/*pharmacology[MESH] |Glycoside Hydrolases/*antagonists & inhibitors[MESH] |Heterocyclic Compounds, 1-Ring/chemical synthesis/chemistry/*pharmacology[MESH] |Humans[MESH] |Microbial Sensitivity Tests[MESH] |Models, Biological[MESH] |Models, Molecular[MESH] |Osteoarthritis/*enzymology[MESH] |Severe acute respiratory syndrome-related coronavirus/drug effects[MESH] |Structure-Activity Relationship[MESH] |Substrate Specificity[MESH]Novel five-membered iminocyclitol derivatives as selective and potent (epmc).pdf DeepDyve Pubget Overpricing