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10.1208/aapsj070239 http://scihub22266oqcxt.onion/10.1208/aapsj070239 16353918!2750976!16353918     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       AAPS+J 2005 ; 7 (2): E383-9 Nephropedia Template TP {{tp|p=16353918|t=2005. Population pharmacokinetics/pharmacodynamics of anesthetics |pdf=|usr=}}{{16353918}} gab.com Text Population pharmacokinetics/pharmacodynamics of anesthetics JO: AAPS J http://www.kidney.de/pget.php?&tw=1&pmid=16353918 #FOAvip In this article we review how population pharmacokinetic/pharmacodynamic (PD) modeling has evolved in the specialty of anesthesiology, how anesthesiology benefited from the mixed-effects approach, and which features of modeling need careful attention. Key articles from the anesthesiology literature are selected to discuss the modeling of typical anesthesiological PD end points, such as level of consciousness and analgesia, interactions between hypnotics and analgesics, estimation with poor and sometimes rich data sets from populations of various sizes, covariate detection, covariances between random effects, and Bayesian forecasting. Twit Text FOAVip Population pharmacokinetics/pharmacodynamics of anesthetics ????AAPS J http://www.kidney.de/pget.php?&tw=1&pmid=16353918 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=16353918 #FOAvip English Wikipedia <ref>{{Cite pmid|16353918}}</ref> Population pharmacokinetics/pharmacodynamics of anesthetics #MMPMID16353918 Olofsen E; Dahan A AAPS J 2005[Oct]; 7 (2): E383-9 PMID16353918show ga In this article we review how population pharmacokinetic/pharmacodynamic (PD) modeling has evolved in the specialty of anesthesiology, how anesthesiology benefited from the mixed-effects approach, and which features of modeling need careful attention. Key articles from the anesthesiology literature are selected to discuss the modeling of typical anesthesiological PD end points, such as level of consciousness and analgesia, interactions between hypnotics and analgesics, estimation with poor and sometimes rich data sets from populations of various sizes, covariate detection, covariances between random effects, and Bayesian forecasting. |*Models, Biological[MESH] |Anesthetics/*pharmacokinetics[MESH] |Animals[MESH] |Humans[MESH]Population pharmacokinetics/pharmacodynamics of anesthetics (epmc).pdf DeepDyve Pubget Overpricing