Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText.
Kick-your-searchterm to multiple Engines kick-your-query now !>
A dictionary by aggregated review articles of nephrology, medicine and the life sciences
Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

suck abstract from ncbi


10.1152/ajprenal.00118.2005

http://scihub22266oqcxt.onion/10.1152/ajprenal.00118.2005
suck pdf from google scholar
16275743!ä!16275743
PDF vom PMID16275743 :   free

suck abstract from ncbi

pmid16275743
Nephropedia Template TP

gab.com Text

Twit Text FOAVip

Twit Text #

English Wikipedia


  • An incredible decade for the primary cilium: a look at a once-forgotten organelle #MMPMID16275743
  • Davenport JR; Yoder BK
  • Am J Physiol Renal Physiol 2005[Dec]; 289 (6): F1159-69 PMID16275743show ga
  • Since the discovery that numerous proteins involved in mammalian disease localize to the basal bodies and cilia, these organelles have emerged from relative obscurity to the center of intense research efforts in an expanding number of disease- and developmental-related fields. Our understanding of the association between cilia and human disease has benefited substantially from the use of lower organisms such as Chlamydomonas and Caenorhabditis elegans and the availability of murine models and cell culture. These research endeavors led to the discovery that loss of normal ciliary function in mammals is responsible for cystic and noncystic pathology in the kidney, liver, brain, and pancreas, as well as severe developmental patterning abnormalities. In addition, the localization of proteins involved in rare human disorders such as Bardet-Biedl syndrome has suggested that cilia-related dysfunction may play a role in modern human epidemics such as hypertension, obesity, and diabetes. Although we have made great advances in demonstrating the importance of cilia over the past decade, the physiological role that this organelle plays in most tissues remains elusive. Research focused on addressing this issue will be of critical importance for a further understanding of how ciliary dysfunction can lead to such severe disease and developmental pathologies.
  • |Adaptor Proteins, Signal Transducing[MESH]
  • |Animals[MESH]
  • |Cilia/*physiology/ultrastructure[MESH]
  • |Cytoskeletal Proteins[MESH]
  • |Embryonic Development/physiology[MESH]
  • |Humans[MESH]
  • |Intracellular Signaling Peptides and Proteins/genetics[MESH]
  • |Kartagener Syndrome/genetics[MESH]
  • |Kidney Diseases/physiopathology[MESH]
  • |Kinesins/genetics[MESH]
  • |Liver/physiology/ultrastructure[MESH]
  • |Mice[MESH]
  • |Pancreas/physiology/ultrastructure[MESH]
  • |Polycystic Kidney Diseases/genetics[MESH]
  • |Retina/physiology/ultrastructure[MESH]


  • DeepDyve
  • Pubget Overpricing
  • suck abstract from ncbi

    F1159 6.289 2005