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10.1152/japplphysiol.00362.2005 http://scihub22266oqcxt.onion/10.1152/japplphysiol.00362.2005 15920100!ä!15920100 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 227.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Appl+Physiol+(1985) 2005 ; 99 (4): 1286-92 Nephropedia Template TP {{tp|p=15920100|t=2005. Epithelial lining fluid solute concentrations in chronic obstructive lung disease patients and normal subjects |pdf=|usr=}}{{15920100}} gab.com Text Epithelial lining fluid solute concentrations in chronic obstructive lung disease patients and normal subjects JO: J Appl Physiol (1985) http://www.kidney.de/pget.php?&tw=1&pmid=15920100 #FOAvip The exhaled breath condensate (EBC) method represents a new, noninvasive way to detect inflammatory and metabolic markers in the fluid that covers the airways [epithelial lining fluid (ELF)]. However, respiratory droplets represent only a very small and variable fraction of the EBC, most (approximately 99.99%) of which is water vapor. Our objective was to show that ELF concentrations could be calculated from EBC values by using any of three dilutional indicators (urea, total cations, and conductivity) in nine normal and nine chronic obstructive lung disease (COPD) subjects. EBC concentrations of Na(+), K(+), Ca(2+), Mg(2+), total cations, urea, and conductivity varied over a 10-fold range among individuals, but concentrations of these constituents (except Ca(2+)) remained well correlated (r(2) = 0.44-0.83, P < 0.001). Dilution (D) of respiratory droplets in water vapor was calculated by dividing plasma concentrations of the dilutional indicators by EBC concentrations. Estimates of D were not significantly different among these indicators, and urea D averaged 10,800 +/- 2,100 (SE) in normal and 12,600 +/- 3,300 in COPD subjects. Although calculated Na(+) concentrations in the ELF were less than one-half those in plasma, and concentrations of K(+), Ca(2+), and Mg(2+) exceeded those in plasma, total cation concentrations in ELF were not significantly different from those in plasma, indicating that ELF is isotonic in both normal and COPD subjects. EBC amylase concentrations (measured with an ultrasensitive procedure) indicated that saliva represented <10% of the respiratory (ELF) droplets in all but three samples. Dilutional and salivary markers are essential for interpretation of EBC studies. Twit Text FOAVip Epithelial lining fluid solute concentrations in chronic obstructive lung disease patients and normal subjects ????J Appl Physiol (1985) http://www.kidney.de/pget.php?&tw=1&pmid=15920100 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=15920100 #FOAvip English Wikipedia <ref>{{Cite pmid|15920100}}</ref> Epithelial lining fluid solute concentrations in chronic obstructive lung disease patients and normal subjects #MMPMID15920100 Effros RM; Peterson B; Casaburi R; Su J; Dunning M; Torday J; Biller J; Shaker R J Appl Physiol (1985) 2005[Oct]; 99 (4): 1286-92 PMID15920100show ga The exhaled breath condensate (EBC) method represents a new, noninvasive way to detect inflammatory and metabolic markers in the fluid that covers the airways [epithelial lining fluid (ELF)]. However, respiratory droplets represent only a very small and variable fraction of the EBC, most (approximately 99.99%) of which is water vapor. Our objective was to show that ELF concentrations could be calculated from EBC values by using any of three dilutional indicators (urea, total cations, and conductivity) in nine normal and nine chronic obstructive lung disease (COPD) subjects. EBC concentrations of Na(+), K(+), Ca(2+), Mg(2+), total cations, urea, and conductivity varied over a 10-fold range among individuals, but concentrations of these constituents (except Ca(2+)) remained well correlated (r(2) = 0.44-0.83, P < 0.001). Dilution (D) of respiratory droplets in water vapor was calculated by dividing plasma concentrations of the dilutional indicators by EBC concentrations. Estimates of D were not significantly different among these indicators, and urea D averaged 10,800 +/- 2,100 (SE) in normal and 12,600 +/- 3,300 in COPD subjects. Although calculated Na(+) concentrations in the ELF were less than one-half those in plasma, and concentrations of K(+), Ca(2+), and Mg(2+) exceeded those in plasma, total cation concentrations in ELF were not significantly different from those in plasma, indicating that ELF is isotonic in both normal and COPD subjects. EBC amylase concentrations (measured with an ultrasensitive procedure) indicated that saliva represented <10% of the respiratory (ELF) droplets in all but three samples. Dilutional and salivary markers are essential for interpretation of EBC studies. |Aged[MESH] |Body Fluids/*metabolism[MESH] |Body Water/metabolism[MESH] |Calcium/blood/metabolism[MESH] |Case-Control Studies[MESH] |Epithelium/metabolism[MESH] |Exhalation[MESH] |Female[MESH] |Humans[MESH] |Isotonic Solutions/metabolism[MESH] |Lung/*metabolism[MESH] |Magnesium/blood/metabolism[MESH] |Male[MESH] |Middle Aged[MESH] |Osmolar Concentration[MESH] |Potassium/blood/metabolism[MESH] |Pulmonary Disease, Chronic Obstructive/*metabolism[MESH] |Saliva/metabolism[MESH]Epithelial lining fluid solute concentrations in chronic obstructive l(epmc).pdf DeepDyve Pubget Overpricing