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Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 J+Am+Soc+Nephrol 2005 ; 16 (2): 305-12 Nephropedia Template TP
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Caenorhabditis elegans as a model to study renal development and disease: sexy cilia #MMPMID15647338
Barr MM
J Am Soc Nephrol 2005[Feb]; 16 (2): 305-12 PMID15647338show ga
The nematode Caenorhabditis elegans has no kidney per se, yet "the worm" has proved to be an excellent model to study renal-related issues, including tubulogenesis of the excretory canal, membrane transport and ion channel function, and human genetic diseases including autosomal dominant polycystic kidney disease (ADPKD). The goal of this review is to explain how C. elegans has provided insight into cilia development, cilia function, and human cystic kidney diseases.