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10.1016/j.jmb.2004.06.016 http://scihub22266oqcxt.onion/10.1016/j.jmb.2004.06.016 15312778!7127270!15312778     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Mol+Biol 2004 ; 341 (1): 271-9 Nephropedia Template TP {{tp|p=15312778|t=2004. Characterization of the 3a protein of SARS-associated coronavirus in infected vero E6 cells and SARS patients |pdf=|usr=}}{{15312778}} gab.com Text Characterization of the 3a protein of SARS-associated coronavirus in infected vero E6 cells and SARS patients JO: J Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=15312778 #FOAvip Proteomics was used to identify a protein encoded by ORF 3a in a SARS-associated coronavirus (SARS-CoV). Immuno-blotting revealed that interchain disulfide bonds might be formed between this protein and the spike protein. ELISA indicated that sera from SARS patients have significant positive reactions with synthesized peptides derived from the 3a protein. These results are concordant with that of a spike protein-derived peptide. A tendency exists for co-mutation between the 3a protein and the spike protein of SARS-CoV isolates, suggesting that the function of the 3a protein correlates with the spike protein. Taken together, the 3a protein might be tightly correlated to the spike protein in the SARS-CoV functions. The 3a protein may serve as a new clinical marker or drug target for SARS treatment. Twit Text FOAVip Characterization of the 3a protein of SARS-associated coronavirus in infected vero E6 cells and SARS patients ????J Mol Biol http://www.kidney.de/pget.php?&tw=1&pmid=15312778 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=15312778 #FOAvip English Wikipedia <ref>{{Cite pmid|15312778}}</ref> Characterization of the 3a protein of SARS-associated coronavirus in infected vero E6 cells and SARS patients #MMPMID15312778 Zeng R; Yang RF; Shi MD; Jiang MR; Xie YH; Ruan HQ; Jiang XS; Shi L; Zhou H; Zhang L; Wu XD; Lin Y; Ji YY; Xiong L; Jin Y; Dai EH; Wang XY; Si BY; Wang J; Wang HX; Wang CE; Gan YH; Li YC; Cao JT; Zuo JP; Shan SF; Xie E; Chen SH; Jiang ZQ; Zhang X; Wang Y; Pei G; Sun B; Wu JR J Mol Biol 2004[Jul]; 341 (1): 271-9 PMID15312778show ga Proteomics was used to identify a protein encoded by ORF 3a in a SARS-associated coronavirus (SARS-CoV). Immuno-blotting revealed that interchain disulfide bonds might be formed between this protein and the spike protein. ELISA indicated that sera from SARS patients have significant positive reactions with synthesized peptides derived from the 3a protein. These results are concordant with that of a spike protein-derived peptide. A tendency exists for co-mutation between the 3a protein and the spike protein of SARS-CoV isolates, suggesting that the function of the 3a protein correlates with the spike protein. Taken together, the 3a protein might be tightly correlated to the spike protein in the SARS-CoV functions. The 3a protein may serve as a new clinical marker or drug target for SARS treatment. |Animals[MESH] |Chlorocebus aethiops[MESH] |Disulfides/metabolism[MESH] |Humans[MESH] |Membrane Glycoproteins/metabolism[MESH] |Phylogeny[MESH] |Proteomics[MESH] |Sequence Analysis, Protein[MESH] |Severe acute respiratory syndrome-related coronavirus/chemistry/genetics/*metabolism[MESH] |Spike Glycoprotein, Coronavirus[MESH] |Vero Cells[MESH] |Viral Envelope Proteins/metabolism[MESH] |Viral Proteins/chemistry/genetics/*metabolism[MESH]Characterization of the 3a protein of SARS-associated coronavirus in i(epmc).pdf DeepDyve Pubget Overpricing