Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1086/382963 http://scihub22266oqcxt.onion/10.1086/382963 15122524!ä!15122524 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Infect+Dis 2004 ; 189 (10): 1873-80 Nephropedia Template TP {{tp|p=15122524|t=2004. B cell memory is directed toward conformational epitopes of parvovirus B19 capsid proteins and the unique region of VP1 |pdf=|usr=}}{{15122524}} gab.com Text B cell memory is directed toward conformational epitopes of parvovirus B19 capsid proteins and the unique region of VP1 JO: J Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=15122524 #FOAvip BACKGROUND: Loss of antibody reactivity against linear epitopes of parvovirus B19 (B19) capsid proteins VP1 and VP2 occurs after infection; however, it is unclear whether B cell memory is established against linear epitopes. METHODS: B cell enzyme-linked immunospot assay was used to evaluate B19-specific B cell memory in volunteer donors (n=22). RESULTS: B cell memory is maintained against conformational epitopes of VP2 and is absent against linear epitopes of VP2. Individuals seronegative for IgG against the unique region of VP1 have detectable B cell memory, with the potential to mount a humoral response on reexposure to B19. Conversely, in mice immunized with VP2, long-lasting IgG against linear epitopes of VP2 and a strong B cell-memory response are observed. CONCLUSIONS: B cell memory is established and maintained against conformational epitopes of VP2 and against linear epitopes of VP1 but not against linear epitopes of VP2. These findings further our understanding of the immune response to B19 and suggest that analysis of B19-specific B cell memory merits consideration for future B19-vaccine studies. Twit Text FOAVip B cell memory is directed toward conformational epitopes of parvovirus B19 capsid proteins and the unique region of VP1 ????J Infect Dis http://www.kidney.de/pget.php?&tw=1&pmid=15122524 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=15122524 #FOAvip English Wikipedia <ref>{{Cite pmid|15122524}}</ref> B cell memory is directed toward conformational epitopes of parvovirus B19 capsid proteins and the unique region of VP1 #MMPMID15122524 Corcoran A; Mahon BP; Doyle S J Infect Dis 2004[May]; 189 (10): 1873-80 PMID15122524show ga BACKGROUND: Loss of antibody reactivity against linear epitopes of parvovirus B19 (B19) capsid proteins VP1 and VP2 occurs after infection; however, it is unclear whether B cell memory is established against linear epitopes. METHODS: B cell enzyme-linked immunospot assay was used to evaluate B19-specific B cell memory in volunteer donors (n=22). RESULTS: B cell memory is maintained against conformational epitopes of VP2 and is absent against linear epitopes of VP2. Individuals seronegative for IgG against the unique region of VP1 have detectable B cell memory, with the potential to mount a humoral response on reexposure to B19. Conversely, in mice immunized with VP2, long-lasting IgG against linear epitopes of VP2 and a strong B cell-memory response are observed. CONCLUSIONS: B cell memory is established and maintained against conformational epitopes of VP2 and against linear epitopes of VP1 but not against linear epitopes of VP2. These findings further our understanding of the immune response to B19 and suggest that analysis of B19-specific B cell memory merits consideration for future B19-vaccine studies. |Adult[MESH] |Animals[MESH] |Antibodies, Viral/blood[MESH] |B-Lymphocytes/*immunology[MESH] |Capsid Proteins/*immunology[MESH] |Epitopes, B-Lymphocyte/*immunology[MESH] |Humans[MESH] |Immunoenzyme Techniques[MESH] |Immunoglobulin G/blood[MESH] |Immunologic Memory/*immunology[MESH] |Mice[MESH] |Mice, Inbred BALB C[MESH] |Parvoviridae Infections/*immunology[MESH] |Parvovirus B19, Human/*immunology[MESH] |Protein Conformation[MESH]B cell memory is directed toward conformational epitopes of parvovirus(epmc).pdf DeepDyve Pubget Overpricing