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suck abstract from ncbi


10.1242/dev.01089

http://scihub22266oqcxt.onion/10.1242/dev.01089
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15023929!ä!15023929

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suck abstract from ncbi

pmid15023929      Development 2004 ; 131 (7): 1449-62
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  • Branching morphogenesis and kidney disease #MMPMID15023929
  • Shah MM; Sampogna RV; Sakurai H; Bush KT; Nigam SK
  • Development 2004[Apr]; 131 (7): 1449-62 PMID15023929show ga
  • Branching morphogenesis in the kidney is a tightly regulated, complex process and its disruption potentially can lead to a broad spectrum of diseases, ranging from rare hereditary syndromes to common conditions such as hypertension and chronic kidney failure. This review synthesizes data on branching during kidney development derived from in vitro and in vivo rodent studies and to apply them to human diseases. It discusses how the broad organization of molecular interactions during kidney development might provide a mechanistic framework for understanding disorders related to aberrant branching.
  • |Animals[MESH]
  • |Disease Models, Animal[MESH]
  • |Gene Expression Regulation, Developmental[MESH]
  • |Heparan Sulfate Proteoglycans/metabolism[MESH]
  • |Humans[MESH]
  • |Kidney/*anatomy & histology/*embryology/pathology/physiology[MESH]
  • |Molecular Structure[MESH]
  • |Morphogenesis/*physiology[MESH]


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