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10.1016/S0022-3999(03)00381-7

http://scihub22266oqcxt.onion/10.1016/S0022-3999(03)00381-7
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14987977!ä!14987977

suck abstract from ncbi


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pmid14987977      J+Psychosom+Res 2004 ; 56 (1): 145-8
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  • Microcirculatory assessment of vascular acrosyndrome in anorexia nervosa and analysis of manifestation factors #MMPMID14987977
  • Klein-Weigel P; Rein P; Kronenberg F; List E; Kinzl J; Biebl W; Fraedrich G
  • J Psychosom Res 2004[Jan]; 56 (1): 145-8 PMID14987977show ga
  • OBJECTIVE: Acrocyanosis (AC) is a common manifestation of starving syndrome in anorexia nervosa. We characterized microvascular changes associated with AC and determined discriminating factors between acrally symptomatic and nonsymptomatic patients. METHODS: We examined 34 patients with anorexia nervosa (15 restrictive-anorectic type, 19 binge-eating/purging type, duration 1-25 years). Nineteen were symptomatic (SP) and 15 were nonsymptomatic (NSP). All underwent photo-pletysmography, sonography of the brachial artery, capillary microscopy and laboratory analysis. RESULTS: Disease characteristics and body mass index did not differ between SP and NSP. In SP more dilated efferent capillary loops and venoles were present (P<.001) and capillary flow velocities were reduced (0.21+/-0.12 ml/min vs. 0.34+/-0.15 ml/min; P=.015). Flow-mediated and nitroglycerin-induced dilatation showed no differences. Symptomatic patients had lower leukocyte counts (P=.008), lower eosinophils (P=.003) and lower LDL (P=.045) concentrations. A logistic regression model identified only leukocytes (P=.017) and eosinophils (P=.023) to be associated with AC. CONCLUSIONS: In acrally symptomatic patients the typical microvascular features of AC are present. AC is associated with lower leukocyte counts and lower eosinophils.
  • |Anorexia Nervosa/diagnosis/*physiopathology/therapy[MESH]
  • |Body Mass Index[MESH]
  • |Capillaries/pathology[MESH]
  • |Cholesterol/blood[MESH]
  • |Energy Intake[MESH]
  • |Eosinophils[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Leukocyte Count[MESH]
  • |Logistic Models[MESH]
  • |Male[MESH]


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