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10.1002/dvdy.10371

http://scihub22266oqcxt.onion/10.1002/dvdy.10371
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14579389!ä!14579389

suck abstract from ncbi


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pmid14579389      Dev+Dyn 2003 ; 228 (3): 514-22
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  • Zebrafish pronephros: a model for understanding cystic kidney disease #MMPMID14579389
  • Hostetter CL; Sullivan-Brown JL; Burdine RD
  • Dev Dyn 2003[Nov]; 228 (3): 514-22 PMID14579389show ga
  • The embryonic kidney of the zebrafish is the pronephros. The ease of genetic analysis and experimentation in zebrafish, coupled with the simplicity of the pronephros, make the zebrafish an ideal model system for studying kidney development and function. Several mutations have been isolated in zebrafish genetic screens that result in cyst formation in the pronephros. Cloning and characterization of these mutations will provide insight into kidney development but may also provide understanding of the molecular basis of cystic kidney diseases. In this review, we focus on the zebrafish as a model for understanding cystic kidney disease and the links between cystic kidney disease and left-right patterning.
  • |*Kidney Diseases, Cystic[MESH]
  • |Animals[MESH]
  • |Body Patterning/*physiology[MESH]
  • |Kidney/abnormalities/*embryology[MESH]
  • |Models, Animal[MESH]
  • |Morphogenesis[MESH]


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