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10.1007/s00428-003-0898-8 http://scihub22266oqcxt.onion/10.1007/s00428-003-0898-8 14551766!ä!14551766 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Virchows+Arch 2004 ; 444 (1): 36-42 Nephropedia Template TP {{tp|p=14551766|t=2004. The role of M cells of human nasopharyngeal lymphoid tissue in influenza virus sampling |pdf=|usr=}}{{14551766}} gab.com Text The role of M cells of human nasopharyngeal lymphoid tissue in influenza virus sampling JO: Virchows Arch http://www.kidney.de/pget.php?&tw=1&pmid=14551766 #FOAvip Little is known about the role of the M cells of human nasopharyngeal lymphoid tissue in the sampling of viruses that cause respiratory infections. To clarify whether M cells could function as a gateway for influenza virus into human nasopharyngeal lymphoid tissue, excised adenoid tissue was incubated in media containing influenza A virus for 30, 60, and 90 min, respectively. Transmission electron microscopic observation revealed that many influenza viruses adhered to M cell surfaces and were taken up into the cytoplasmic vesicles of M cells after 30 min incubation; the viruses had been transported into enfolded lymphoid cells after 60 min incubation. By staining M cells with Sambucus nigra lectin, which specifically recognizes the NeuAcalpha2,6 Gal linkage of sialoprotein, it was also found that abundant receptors for the human influenza virus are present on the M cell surface. Our findings indicated that M cells of human nasopharyngeal tonsils function as a major port for influenza A virus entry and that the virus could be efficiently transferred to enfolded macrophages and lymphoid cells by M cells. The transport of influenza viruses to lymphoid cells by M cells may promote antigen delivery to the immune system, and these findings may be important for systemic delivery of those influenza viruses that have the capacity to productively infect cells outside of the respiratory tract. Twit Text FOAVip The role of M cells of human nasopharyngeal lymphoid tissue in influenza virus sampling ????Virchows Arch http://www.kidney.de/pget.php?&tw=1&pmid=14551766 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=14551766 #FOAvip English Wikipedia <ref>{{Cite pmid|14551766}}</ref> The role of M cells of human nasopharyngeal lymphoid tissue in influenza virus sampling #MMPMID14551766 Fujimura Y; Takeda M; Ikai H; Haruma K; Akisada T; Harada T; Sakai T; Ohuchi M Virchows Arch 2004[Jan]; 444 (1): 36-42 PMID14551766show ga Little is known about the role of the M cells of human nasopharyngeal lymphoid tissue in the sampling of viruses that cause respiratory infections. To clarify whether M cells could function as a gateway for influenza virus into human nasopharyngeal lymphoid tissue, excised adenoid tissue was incubated in media containing influenza A virus for 30, 60, and 90 min, respectively. Transmission electron microscopic observation revealed that many influenza viruses adhered to M cell surfaces and were taken up into the cytoplasmic vesicles of M cells after 30 min incubation; the viruses had been transported into enfolded lymphoid cells after 60 min incubation. By staining M cells with Sambucus nigra lectin, which specifically recognizes the NeuAcalpha2,6 Gal linkage of sialoprotein, it was also found that abundant receptors for the human influenza virus are present on the M cell surface. Our findings indicated that M cells of human nasopharyngeal tonsils function as a major port for influenza A virus entry and that the virus could be efficiently transferred to enfolded macrophages and lymphoid cells by M cells. The transport of influenza viruses to lymphoid cells by M cells may promote antigen delivery to the immune system, and these findings may be important for systemic delivery of those influenza viruses that have the capacity to productively infect cells outside of the respiratory tract. |Adolescent[MESH] |Child[MESH] |Child, Preschool[MESH] |Cytoplasm/ultrastructure[MESH] |Female[MESH] |Humans[MESH] |Influenza A virus/*isolation & purification/ultrastructure[MESH] |Lymphocytes/virology[MESH] |Lymphoid Tissue/ultrastructure/*virology[MESH] |Macrophages/virology[MESH] |Male[MESH] |Microscopy, Electron[MESH] |Microscopy, Immunoelectron[MESH] |Nasopharynx/ultrastructure/*virology[MESH] |Palatine Tonsil/chemistry/ultrastructure/virology[MESH] |Respiratory Tract Infections/virology[MESH] |Sialoglycoproteins/analysis[MESH]The role of M cells of human nasopharyngeal lymphoid tissue in influen(epmc).pdf DeepDyve Pubget Overpricing