Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1016/j.str.2003.08.011 http://scihub22266oqcxt.onion/10.1016/j.str.2003.08.011 14527390!ä!14527390 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Structure 2003 ; 11 (10): 1219-26 Nephropedia Template TP {{tp|p=14527390|t=2003. Crystal structure of the borna disease virus nucleoprotein |pdf=|usr=}}{{14527390}} gab.com Text Crystal structure of the borna disease virus nucleoprotein JO: Structure http://www.kidney.de/pget.php?&tw=1&pmid=14527390 #FOAvip Borna disease virus (BDV) causes an infection of the central nervous system in a wide range of vertebrates, which can fatally progress to an immune-mediated disease, called Borna disease. BDV is a member of the Mononegavirales, which also includes the highly infectious measles and Ebola viruses. The viral nucleoproteins are central to transcription, replication, and packaging of the RNA genome. We present the X-ray structure of the BDV nucleoprotein determined at 1.76 A resolution. The structure reveals a novel fold, organized into two distinct domains, and an assembly into a planar homotetramer. Surface potential calculations strongly support an RNA binding model with the RNA wrapping around the outside of the tetramer, although a positively charged central channel in the tetramer could fit single-stranded RNA in an alternative binding mode. This first structure of an RNA virus nucleoprotein provides a paradigmatic model for RNA packaging and replication of single-stranded RNA viruses. Twit Text FOAVip Crystal structure of the borna disease virus nucleoprotein ????Structure http://www.kidney.de/pget.php?&tw=1&pmid=14527390 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=14527390 #FOAvip English Wikipedia <ref>{{Cite pmid|14527390}}</ref> Crystal structure of the borna disease virus nucleoprotein #MMPMID14527390 Rudolph MG; Kraus I; Dickmanns A; Eickmann M; Garten W; Ficner R Structure 2003[Oct]; 11 (10): 1219-26 PMID14527390show ga Borna disease virus (BDV) causes an infection of the central nervous system in a wide range of vertebrates, which can fatally progress to an immune-mediated disease, called Borna disease. BDV is a member of the Mononegavirales, which also includes the highly infectious measles and Ebola viruses. The viral nucleoproteins are central to transcription, replication, and packaging of the RNA genome. We present the X-ray structure of the BDV nucleoprotein determined at 1.76 A resolution. The structure reveals a novel fold, organized into two distinct domains, and an assembly into a planar homotetramer. Surface potential calculations strongly support an RNA binding model with the RNA wrapping around the outside of the tetramer, although a positively charged central channel in the tetramer could fit single-stranded RNA in an alternative binding mode. This first structure of an RNA virus nucleoprotein provides a paradigmatic model for RNA packaging and replication of single-stranded RNA viruses. |Amino Acid Sequence[MESH] |Binding Sites[MESH] |Borna disease virus/*chemistry/physiology[MESH] |Capsid Proteins/*chemistry/physiology[MESH] |Molecular Chaperones/metabolism[MESH] |Molecular Sequence Data[MESH] |Nucleoproteins/*chemistry/physiology[MESH] |Phosphoproteins/metabolism[MESH] |Protein Structure, Tertiary[MESH] |RNA/metabolism[MESH]Crystal structure of the borna disease virus nucleoprotein (epmc).pdf DeepDyve Pubget Overpricing