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10.1086/378592 http://scihub22266oqcxt.onion/10.1086/378592 13680523/?report=reader!1180613!13680523     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Am+J+Hum+Genet 2003 ; 73 (4): 933-8 Nephropedia Template TP {{tp|p=13680523|t=2003. Genomic imprinting and linkage test for quantitative-trait Loci in extended pedigrees |pdf=|usr=}}{{13680523}} gab.com Text Genomic imprinting and linkage test for quantitative-trait Loci in extended pedigrees JO: Am J Hum Genet http://www.kidney.de/pget.php?&tw=1&pmid=13680523 #FOAvip Genomic imprinting is a mechanism in which only one of the two copies of a gene is expressed. Some genes that affect development and behavior in mammals are known to be imprinted. Deregulation of imprinted genes has been found in a number of human diseases. Incorporating imprinting information into linkage analysis results in a more powerful test for linkage. Here, we propose an efficient method to test for linkage and imprinting of quantitative traits in extended pedigrees. We compared the results obtained by using the extended-pedigree-analysis approach proposed in this study with other existing approaches. We found that the proposed method is more powerful and uses extended-pedigree information most efficiently. Twit Text FOAVip Genomic imprinting and linkage test for quantitative-trait Loci in extended pedigrees ????Am J Hum Genet http://www.kidney.de/pget.php?&tw=1&pmid=13680523 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=13680523 #FOAvip English Wikipedia <ref>{{Cite pmid|13680523}}</ref> Genomic imprinting and linkage test for quantitative-trait Loci in extended pedigrees #MMPMID13680523 Shete S; Zhou X; Amos CI Am J Hum Genet 2003[Oct]; 73 (4): 933-8 PMID13680523show ga Genomic imprinting is a mechanism in which only one of the two copies of a gene is expressed. Some genes that affect development and behavior in mammals are known to be imprinted. Deregulation of imprinted genes has been found in a number of human diseases. Incorporating imprinting information into linkage analysis results in a more powerful test for linkage. Here, we propose an efficient method to test for linkage and imprinting of quantitative traits in extended pedigrees. We compared the results obtained by using the extended-pedigree-analysis approach proposed in this study with other existing approaches. We found that the proposed method is more powerful and uses extended-pedigree information most efficiently. |*Genetic Linkage[MESH] |*Quantitative Trait Loci[MESH] |Female[MESH] |Genetic Diseases, Inborn/genetics[MESH] |Genomic Imprinting/*genetics[MESH] |Humans[MESH] |Male[MESH] |Models, Genetic[MESH] |Models, Statistical[MESH]Genomic imprinting and linkage test for quantitative-trait Loci in ext(epmc).pdf DeepDyve Pubget Overpricing