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10.1111/j.1365-2710.1992.tb01285.x

http://scihub22266oqcxt.onion/10.1111/j.1365-2710.1992.tb01285.x
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1353501!ä!1353501

suck abstract from ncbi

pmid1353501      J+Clin+Pharm+Ther 1992 ; 17 (3): 155-64
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  • Metabolic effects of beta 2-agonists #MMPMID1353501
  • Haffner CA; Kendall MJ
  • J Clin Pharm Ther 1992[Jun]; 17 (3): 155-64 PMID1353501show ga
  • Catecholamines produce a number of biochemical changes most of which result from stimulation of beta 2-receptors. Interest in these metabolic effects has increased recently as a consequence of the concern over the relatively high mortality from acute asthma attacks. In this review the data on the impact of beta 2-agonists on glucose production, insulin release and lipolysis are presented. Thereafter the subject of hypokalaemia, the mechanism for its production by beta 2-agonists and its relevance to cardiac arrhythmias are considered in detail. Finally the fall in plasma magnesium and the possible role of beta 2-agonists in the production of lactic acidosis are discussed.
  • |Acidosis, Lactic/chemically induced[MESH]
  • |Acute Disease[MESH]
  • |Adrenergic beta-Agonists/*pharmacology/therapeutic use[MESH]
  • |Albuterol/pharmacology[MESH]
  • |Asthma/drug therapy[MESH]
  • |Female[MESH]
  • |Glucose/*biosynthesis[MESH]
  • |Humans[MESH]
  • |Hypokalemia/chemically induced[MESH]
  • |Insulin Secretion[MESH]
  • |Insulin/*metabolism[MESH]
  • |Lipolysis/*drug effects[MESH]
  • |Magnesium/blood[MESH]


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