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1348867!ä!1348867

suck abstract from ncbi


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pmid1348867      Kokyu+To+Junkan 1992 ; 40 (2): 195-8
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  • A case of congenital long QT syndrome associated with T wave alternans #MMPMID1348867
  • Motoyasu M; Nishikawa H; Shimizu Y; Aoki T; Ono N; Unno M; Kakuta Y; Yazu T; Kasai A; Yamakado T; et al.
  • Kokyu To Junkan 1992[Feb]; 40 (2): 195-8 PMID1348867show ga
  • A case was presented in which a rare T wave alternans occurred in association with congenital long QT syndrome. A 71-year-old woman, who had experienced several syncopal attacks per year for the previous forty years, was admitted for further evaluation of the syncope. She had a family history of sudden death (sister) and QT prolongation (son). Electrocardiogram showed a corrected QT interval of 0.68 seconds. Treadmill exercise-tolerance test revealed both T wave alternans immediately after exercise and torsades de pointes 150 seconds after exercise. The syncope was induced by the mental excitation. A prolonged corrected QT interval reduced from 0.70 seconds to 0.58 seconds by the correction of her serum potassium and magnesium. The effect of propranolol, verapamil, phenytoin or mexiletine on T wave alternans and ventricular arrhythmia was evaluated by the treadmill exercise-tolerance test. The treatment with propranolol was most effective.
  • |*Electrocardiography[MESH]
  • |Adrenergic beta-Antagonists/therapeutic use[MESH]
  • |Aged[MESH]
  • |Exercise Test[MESH]
  • |Female[MESH]
  • |Humans[MESH]
  • |Long QT Syndrome/*congenital/drug therapy/physiopathology[MESH]
  • |Propranolol/therapeutic use[MESH]
  • |Syncope/drug therapy/etiology[MESH]


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