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10.1002/jmv.10420 http://scihub22266oqcxt.onion/10.1002/jmv.10420 12767014!ä!12767014 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Med+Virol 2003 ; 70 (3): 475-80 Nephropedia Template TP {{tp|p=12767014|t=2003. Ex vivo cytokine responses against parvovirus B19 antigens in previously infected pregnant women |pdf=|usr=}}{{12767014}} gab.com Text Ex vivo cytokine responses against parvovirus B19 antigens in previously infected pregnant women JO: J Med Virol http://www.kidney.de/pget.php?&tw=1&pmid=12767014 #FOAvip Parvovirus B19 infection is a significant cause of fetal death. The aim of this study was to investigate the role of maternal immune status in modulating susceptibility to fetal B19 infection. Peripheral blood was obtained from pregnant women (n = 199) with no clinical evidence of recent B19 infection. Evaluation of ex vivo T cell responses from 149/199 individuals showed significantly higher interferon-gamma levels for seropositive individuals following VP1 (268 +/- 36 versus 103 +/- 19 pg/ml; P = 0.003) and VP2 (242 +/- 42 versus 91 +/- 16 pg/ml; P = 0.01) antigen stimulation. Significantly higher levels of interleukin-2 were also observed in seropositive individuals following both VP1 (P = 0.0003) and VP2 (P = 0.0005) stimulation. The observed Th1 cellular response is lower than that documented previously for non-pregnant individuals and strongly suggests that diminution of the maternal anti-viral immune response may increase susceptibility to fetal B19 infection. Twit Text FOAVip Ex vivo cytokine responses against parvovirus B19 antigens in previously infected pregnant women ????J Med Virol http://www.kidney.de/pget.php?&tw=1&pmid=12767014 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=12767014 #FOAvip English Wikipedia <ref>{{Cite pmid|12767014}}</ref> Ex vivo cytokine responses against parvovirus B19 antigens in previously infected pregnant women #MMPMID12767014 Corcoran A; Mahon BP; McParland P; Davoren A; Doyle S J Med Virol 2003[Jul]; 70 (3): 475-80 PMID12767014show ga Parvovirus B19 infection is a significant cause of fetal death. The aim of this study was to investigate the role of maternal immune status in modulating susceptibility to fetal B19 infection. Peripheral blood was obtained from pregnant women (n = 199) with no clinical evidence of recent B19 infection. Evaluation of ex vivo T cell responses from 149/199 individuals showed significantly higher interferon-gamma levels for seropositive individuals following VP1 (268 +/- 36 versus 103 +/- 19 pg/ml; P = 0.003) and VP2 (242 +/- 42 versus 91 +/- 16 pg/ml; P = 0.01) antigen stimulation. Significantly higher levels of interleukin-2 were also observed in seropositive individuals following both VP1 (P = 0.0003) and VP2 (P = 0.0005) stimulation. The observed Th1 cellular response is lower than that documented previously for non-pregnant individuals and strongly suggests that diminution of the maternal anti-viral immune response may increase susceptibility to fetal B19 infection. |*Capsid Proteins[MESH] |Adolescent[MESH] |Adult[MESH] |Antibodies, Viral/blood[MESH] |Capsid/*immunology[MESH] |Cells, Cultured[MESH] |Female[MESH] |Humans[MESH] |In Vitro Techniques[MESH] |Interferon-gamma/*biosynthesis[MESH] |Interleukin-2/*biosynthesis[MESH] |Leukocytes, Mononuclear[MESH] |Middle Aged[MESH] |Parvoviridae Infections/blood/immunology[MESH] |Parvovirus/*immunology[MESH]Ex vivo cytokine responses against parvovirus B19 antigens in previous(epmc).pdf DeepDyve Pubget Overpricing