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10.1002/dvdy.10205

http://scihub22266oqcxt.onion/10.1002/dvdy.10205
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12508219!ä!12508219

suck abstract from ncbi


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pmid12508219      Dev+Dyn 2003 ; 226 (1): 1-11
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  • Pronephric duct extension in amphibian embryos: migration and other mechanisms #MMPMID12508219
  • Drawbridge J; Meighan CM; Lumpkins R; Kite ME
  • Dev Dyn 2003[Jan]; 226 (1): 1-11 PMID12508219show ga
  • Initiation of excretory system development in all vertebrates requires (1) delamination of the pronephric and pronephric duct rudiments from intermediate mesoderm at the ventral border of anterior somites, and (2) extension of the pronephric duct to the cloaca. Pronephric duct extension is the central event in nephric system development; the pronephric duct differentiates into the tubule that carries nephric filtrate out of the body and induces terminal differentiation of adult kidneys. Early studies concluded that pronephric ducts formed by means of in situ segregation of pronephric duct tissue from lateral mesoderm ventral to the forming somites; more recent studies highlight caudal migration of the pronephric duct as the major morphogenetic mechanism. The purpose of this review is to provide the historical background on studies of the mechanisms of amphibian pronephric duct extension, to review evidence showing that different amphibians perform pronephric duct morphogenesis in different ways, and to suggest future studies that may help illuminate the molecular basis of the mechanisms that have evolved in amphibians to extend the pronephric duct to the cloaca.
  • |Ambystoma/embryology[MESH]
  • |Animals[MESH]
  • |Cell Movement[MESH]
  • |Embryo, Nonmammalian/*cytology[MESH]
  • |In Situ Hybridization[MESH]
  • |Kidney/*embryology[MESH]
  • |Models, Biological[MESH]
  • |Morphogenesis[MESH]
  • |Time Factors[MESH]
  • |Wolffian Ducts/embryology[MESH]


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