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Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Kidney+Int 2002 ; 61 (1): 10-9 Nephropedia Template TP
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Toward an etiological classification of developmental disorders of the kidney and upper urinary tract #MMPMID11786080
Pohl M; Bhatnagar V; Mendoza SA; Nigam SK
Kidney Int 2002[Jan]; 61 (1): 10-9 PMID11786080show ga
Toward an etiological classification of developmental disorders of the kidney and upper urinary tract. There are a large number of developmental disorders and syndromes that affect the kidney and upper urinary tract. These have generally been classified according to morphological criteria established decades ago. Although these classifications have been useful, they are incomplete, including some developmental disorders while excluding others. Here, basic cellular and molecular biology studies of kidney and upper urinary tract development in both rodents and humans are utilized to suggest the basis of a new etiologic, if still tentative, classification scheme. This classification may help to identify candidate genes for human diseases by correlating morphology with pathogenetic mechanisms.