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10.1208/ps030211 http://scihub22266oqcxt.onion/10.1208/ps030211 11741261PreparationandcharacterizationofgelatinsurfacemodifiedPLGAmicrospheres.!2779555!11741261     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       AAPS+PharmSci 2001 ; 3 (2): E11 Nephropedia Template TP {{tp|p=11741261|t=2001. Preparation and characterization of gelatin surface modified PLGA microspheres |pdf=|usr=}}{{11741261}} gab.com Text Preparation and characterization of gelatin surface modified PLGA microspheres JO: AAPS PharmSci http://www.kidney.de/pget.php?&tw=1&pmid=11741261 #FOAvip This study optimized conditions for preparing and characterizing gelatin surface modified poly (lactic-co-glycolic acid) (PLGA) copolymer microspheres and determined this system's interaction with fibronectin. Some gelatin microspheres have an affinity for fibronectin-bearing surfaces; these microspheres exploit the interaction between gelatin and fibronectin. PLGA copolymer microspheres were selected because they have reproducible and slow-release characteristics in vivo. The PLGA microspheres were surface modified with gelatin to impart fibronectin recognition. Dexamethasone was incorporated into these microspheres because dexamethasone is beneficial in chronic human diseases associated with extra fibronectin expression (eg, cardiovascular disease, inflammatory disorders, rheumatoid arthritis). The gelatin surface modified PLGA microspheres (prepared by adsorption, conjugation, and spray coating) were investigated and characterized by encapsulation efficiency, particle size, in vitro release, and affinity for fibronectin. The gelatin-coated PLGA microspheres had higher interaction with fibronectin compared with the other gelatin surface modified PLGA microspheres (adsorption and conjugation). Dexamethasone was released slowly (over 21 days) from gelatin surface modified PLGA microspheres. Twit Text FOAVip Preparation and characterization of gelatin surface modified PLGA microspheres ????AAPS PharmSci http://www.kidney.de/pget.php?&tw=1&pmid=11741261 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=11741261 #FOAvip English Wikipedia <ref>{{Cite pmid|11741261}}</ref> Preparation and characterization of gelatin surface modified PLGA microspheres #MMPMID11741261 Tsung MJ; Burgess DJ AAPS PharmSci 2001[]; 3 (2): E11 PMID11741261show ga This study optimized conditions for preparing and characterizing gelatin surface modified poly (lactic-co-glycolic acid) (PLGA) copolymer microspheres and determined this system's interaction with fibronectin. Some gelatin microspheres have an affinity for fibronectin-bearing surfaces; these microspheres exploit the interaction between gelatin and fibronectin. PLGA copolymer microspheres were selected because they have reproducible and slow-release characteristics in vivo. The PLGA microspheres were surface modified with gelatin to impart fibronectin recognition. Dexamethasone was incorporated into these microspheres because dexamethasone is beneficial in chronic human diseases associated with extra fibronectin expression (eg, cardiovascular disease, inflammatory disorders, rheumatoid arthritis). The gelatin surface modified PLGA microspheres (prepared by adsorption, conjugation, and spray coating) were investigated and characterized by encapsulation efficiency, particle size, in vitro release, and affinity for fibronectin. The gelatin-coated PLGA microspheres had higher interaction with fibronectin compared with the other gelatin surface modified PLGA microspheres (adsorption and conjugation). Dexamethasone was released slowly (over 21 days) from gelatin surface modified PLGA microspheres. |Anti-Inflammatory Agents/chemistry[MESH] |Dexamethasone/chemistry[MESH] |Fibronectins/chemistry[MESH] |Gelatin/*chemistry[MESH] |Lactic Acid/*chemistry[MESH] |Microspheres[MESH] |Particle Size[MESH] |Polyglycolic Acid/*chemistry[MESH] |Polylactic Acid-Polyglycolic Acid Copolymer[MESH] |Polymers/*chemistry[MESH] |Solvents[MESH]Preparation and characterization of gelatin surface modified PLGA micr(epmc).pdf DeepDyve Pubget Overpricing