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10.2165/00128072-200103070-00003

http://scihub22266oqcxt.onion/10.2165/00128072-200103070-00003
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11513282!ä!11513282

suck abstract from ncbi


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pmid11513282      Paediatr+Drugs 2001 ; 3 (7): 509-37
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  • Drug therapy approaches in the treatment of acute severe asthma in hospitalised children #MMPMID11513282
  • DeNicola LK; Gayle MO; Blake KV
  • Paediatr Drugs 2001[]; 3 (7): 509-37 PMID11513282show ga
  • Acute severe paediatric asthma remains a serious and debilitating disease throughout the world. The incidence and mortality from asthma continue to increase. Early, effective and aggressive outpatient therapy is essential in reducing symptoms and preventing life-threatening progression. When complications occur or when the disease progresses to incipient respiratory failure, these children need to be managed in a continuous care facility where aggressive and potentially dangerous interventions can be safely instituted to reverse persistent bronchospasm. The primary drugs for acute severe asthma include oxygen, corticosteroids, salbutamol (albuterol) and anticholinergics. Second-line drugs include heliox, magnesium sulfate, ketamine and inhalational anaesthetics. Future therapies may include furosemide, leukotriene modifiers, antihistamines and phosphodiesterase inhibitors. This review attempts to explore the multitude of medications available with emphasis on pharmacology and pathophysiology.
  • |Asthma/*drug therapy/epidemiology/physiopathology[MESH]
  • |Child[MESH]
  • |Child, Hospitalized/*statistics & numerical data[MESH]


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