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10.3109/10428190009065846

http://scihub22266oqcxt.onion/10.3109/10428190009065846
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11342327!ä!11342327

suck abstract from ncbi


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pmid11342327      Leuk+Lymphoma 2000 ; 39 (3-4): 441-6
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  • Vaccination of a refractory essential monoclonal cryoglobulinemia patient with cryoglobulin-pulsed dendritic cells #MMPMID11342327
  • Maeda M; Inaba S; Nomura A; Tokunaga Y; Sugio Y; Itoh Y; Iino T; Otsuka T; Okamura S; Niho Y
  • Leuk Lymphoma 2000[Oct]; 39 (3-4): 441-6 PMID11342327show ga
  • We vaccinated a refractory essential monoclonal cryoglobulinemia patient with monocyte-derived DCs (Mo-DCs) pulsed with purified cryoglobulin as a tumor antigen. During the vaccinations, his acrocyanosis improved and we were able to reduce the number of hot baths used to treat his symptoms, with no side effects. Furthermore, cryoglobulin-specific proliferative responses were observed after the vaccination. As there was a recurrence of acrocyanosis after the final vaccination, vaccination with Mo-DCs pulsed with purified cryoglobulin would seem to be a useful treatment for refractory essential monoclonal cryoglobulinemia.
  • |Antigens[MESH]
  • |Clone Cells/pathology[MESH]
  • |Cryoglobulinemia/pathology/*therapy[MESH]
  • |Cryoglobulins/immunology[MESH]
  • |Dendritic Cells/immunology/*transplantation[MESH]
  • |Humans[MESH]
  • |Immunotherapy, Adoptive/*methods[MESH]
  • |Lymphocyte Culture Test, Mixed[MESH]
  • |Male[MESH]
  • |Middle Aged[MESH]


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