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Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Leuk+Lymphoma 2000 ; 39 (3-4): 441-6 Nephropedia Template TP
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Vaccination of a refractory essential monoclonal cryoglobulinemia patient with cryoglobulin-pulsed dendritic cells #MMPMID11342327
Maeda M; Inaba S; Nomura A; Tokunaga Y; Sugio Y; Itoh Y; Iino T; Otsuka T; Okamura S; Niho Y
Leuk Lymphoma 2000[Oct]; 39 (3-4): 441-6 PMID11342327show ga
We vaccinated a refractory essential monoclonal cryoglobulinemia patient with monocyte-derived DCs (Mo-DCs) pulsed with purified cryoglobulin as a tumor antigen. During the vaccinations, his acrocyanosis improved and we were able to reduce the number of hot baths used to treat his symptoms, with no side effects. Furthermore, cryoglobulin-specific proliferative responses were observed after the vaccination. As there was a recurrence of acrocyanosis after the final vaccination, vaccination with Mo-DCs pulsed with purified cryoglobulin would seem to be a useful treatment for refractory essential monoclonal cryoglobulinemia.