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10.1001/archpsyc.58.2.165 http://scihub22266oqcxt.onion/10.1001/archpsyc.58.2.165 11177118!ä!11177118 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Arch+Gen+Psychiatry 2001 ; 58 (2): 165-71 Nephropedia Template TP {{tp|p=11177118|t=2001. A separate disease within the syndrome of schizophrenia |pdf=|usr=}}{{11177118}} gab.com Text A separate disease within the syndrome of schizophrenia JO: Arch Gen Psychiatry http://www.kidney.de/pget.php?&tw=1&pmid=11177118 #FOAvip If schizophrenia is a clinical syndrome rather than a single disease, the identification of specific diseases within the syndrome would facilitate the advance of knowledge and the development of more specific treatments. We propose that deficit psychopathology (ie, enduring, idiopathic negative symptoms) defines a group of patients with a disease different from schizophrenia without deficit features, as the deficit and nondeficit groups differ in their signs and symptoms, course, biological correlates, treatment response, and etiologic factors. These differences cannot be attributed to more severe positive psychotic symptoms or a greater duration of illness in the deficit group. The alternative interpretation that patients with deficit schizophrenia are at the severe end of a single disease continuum is not supported by risk factor and biological features data, but there is a need for independent replication of these findings. We suggest a series of studies designed to falsify one of these hypotheses, ie, multiple diseases vs a single disease. Twit Text FOAVip A separate disease within the syndrome of schizophrenia ????Arch Gen Psychiatry http://www.kidney.de/pget.php?&tw=1&pmid=11177118 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=11177118 #FOAvip English Wikipedia <ref>{{Cite pmid|11177118}}</ref> A separate disease within the syndrome of schizophrenia #MMPMID11177118 Kirkpatrick B; Buchanan RW; Ross DE; Carpenter WT Jr Arch Gen Psychiatry 2001[Feb]; 58 (2): 165-71 PMID11177118show ga If schizophrenia is a clinical syndrome rather than a single disease, the identification of specific diseases within the syndrome would facilitate the advance of knowledge and the development of more specific treatments. We propose that deficit psychopathology (ie, enduring, idiopathic negative symptoms) defines a group of patients with a disease different from schizophrenia without deficit features, as the deficit and nondeficit groups differ in their signs and symptoms, course, biological correlates, treatment response, and etiologic factors. These differences cannot be attributed to more severe positive psychotic symptoms or a greater duration of illness in the deficit group. The alternative interpretation that patients with deficit schizophrenia are at the severe end of a single disease continuum is not supported by risk factor and biological features data, but there is a need for independent replication of these findings. We suggest a series of studies designed to falsify one of these hypotheses, ie, multiple diseases vs a single disease. |*Schizophrenic Psychology[MESH] |Antibodies, Viral/analysis[MESH] |Antipsychotic Agents/therapeutic use[MESH] |Borna disease virus/immunology[MESH] |Brain/physiopathology[MESH] |Family[MESH] |Female[MESH] |Humans[MESH] |Male[MESH] |Risk Factors[MESH] |Schizophrenia/classification/*diagnosis/drug therapy[MESH] |Seasons[MESH] |Severity of Illness Index[MESH]A separate disease within the syndrome of schizophrenia (epmc).pdf DeepDyve Pubget Overpricing