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10.1067/mem.2000.111060 http://scihub22266oqcxt.onion/10.1067/mem.2000.111060 11097697!ä!11097697 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Ann+Emerg+Med 2000 ; 36 (6): 572-8 Nephropedia Template TP {{tp|p=11097697|t=2000. A randomized trial of magnesium in the emergency department treatment of children with asthma |pdf=|usr=}}{{11097697}} gab.com Text A randomized trial of magnesium in the emergency department treatment of children with asthma JO: Ann Emerg Med http://www.kidney.de/pget.php?&tw=1&pmid=11097697 #FOAvip STUDY OBJECTIVE: Magnesium sulfate has been shown to benefit asthmatic children and adults with poor responses to initial beta(2)-agonist therapy in the emergency department. We sought to determine whether the routine early administration of high-dose magnesium would benefit moderate to severely ill children with acute asthma. METHODS: This was a randomized, double-blind, placebo-controlled trial of 54 children 1 to 18 years of age who presented to the ED of a tertiary care children's hospital with a moderate to severe asthma exacerbation. After receiving a nebulized albuterol treatment (0.15 mg/kg) and methylprednisolone (1 mg/kg), patients were randomly assigned to receive either 75 mg/kg of magnesium sulfate (maximum 2.5 g) or placebo. Thereafter, all patients were treated with frequent nebulized albuterol following a structured protocol. The main outcome was degree of improvement as assessed by Pulmonary Index scores over 120 minutes. Secondary outcomes included hospitalization rates and time required to meet discharge criteria. RESULTS: The mean change in Pulmonary Index score from baseline to 120 minutes was 2.83 for the magnesium group compared with 2.66 for the placebo group (95% confidence interval -1. 24 to 1.60). Eleven (46%) of 24 magnesium-treated patients were hospitalized compared with 16 (53%) of 30 in the placebo group (95% confidence interval -19% to 34%). There were no statistically significant differences between the groups with respect to time required to meet discharge criteria. CONCLUSION: The routine administration of high-dose magnesium to moderate to severely ill children with asthma, as an adjunct to initial treatment with albuterol and corticosteroids, was not efficacious. Twit Text FOAVip A randomized trial of magnesium in the emergency department treatment of children with asthma ????Ann Emerg Med http://www.kidney.de/pget.php?&tw=1&pmid=11097697 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=11097697 #FOAvip English Wikipedia <ref>{{Cite pmid|11097697}}</ref> A randomized trial of magnesium in the emergency department treatment of children with asthma #MMPMID11097697 Scarfone RJ; Loiselle JM; Joffe MD; Mull CC; Stiller S; Thompson K; Gracely EJ Ann Emerg Med 2000[Dec]; 36 (6): 572-8 PMID11097697show ga STUDY OBJECTIVE: Magnesium sulfate has been shown to benefit asthmatic children and adults with poor responses to initial beta(2)-agonist therapy in the emergency department. We sought to determine whether the routine early administration of high-dose magnesium would benefit moderate to severely ill children with acute asthma. METHODS: This was a randomized, double-blind, placebo-controlled trial of 54 children 1 to 18 years of age who presented to the ED of a tertiary care children's hospital with a moderate to severe asthma exacerbation. After receiving a nebulized albuterol treatment (0.15 mg/kg) and methylprednisolone (1 mg/kg), patients were randomly assigned to receive either 75 mg/kg of magnesium sulfate (maximum 2.5 g) or placebo. Thereafter, all patients were treated with frequent nebulized albuterol following a structured protocol. The main outcome was degree of improvement as assessed by Pulmonary Index scores over 120 minutes. Secondary outcomes included hospitalization rates and time required to meet discharge criteria. RESULTS: The mean change in Pulmonary Index score from baseline to 120 minutes was 2.83 for the magnesium group compared with 2.66 for the placebo group (95% confidence interval -1. 24 to 1.60). Eleven (46%) of 24 magnesium-treated patients were hospitalized compared with 16 (53%) of 30 in the placebo group (95% confidence interval -19% to 34%). There were no statistically significant differences between the groups with respect to time required to meet discharge criteria. CONCLUSION: The routine administration of high-dose magnesium to moderate to severely ill children with asthma, as an adjunct to initial treatment with albuterol and corticosteroids, was not efficacious. |Adolescent[MESH] |Asthma/diagnosis/*drug therapy[MESH] |Child[MESH] |Child, Preschool[MESH] |Confidence Intervals[MESH] |Double-Blind Method[MESH] |Emergency Service, Hospital[MESH] |Emergency Treatment/methods[MESH] |Female[MESH] |Humans[MESH] |Infusions, Intravenous[MESH] |Magnesium Sulfate/*therapeutic use[MESH] |Male[MESH] |Probability[MESH] |Reference Values[MESH] |Respiratory Function Tests[MESH] |Severity of Illness Index[MESH]A randomized trial of magnesium in the emergency department treatment (epmc).pdf DeepDyve Pubget Overpricing