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10.1053/ajkd.2000.17718

http://scihub22266oqcxt.onion/10.1053/ajkd.2000.17718
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11007690!ä!11007690

suck abstract from ncbi


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pmid11007690      Am+J+Kidney+Dis 2000 ; 36 (4): 851-4
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  • Endocapillary proliferative glomerulonephritis in a patient with parvovirus B19 infection #MMPMID11007690
  • Komatsuda A; Ohtani H; Nimura T; Yamaguchi A; Wakui H; Imai H; Miura AB
  • Am J Kidney Dis 2000[Oct]; 36 (4): 851-4 PMID11007690show ga
  • A 45-year-old woman developed acute nephritic syndrome after erythema infectiosum. Laboratory data on admission showed decreased serum C3, C4, and CH50 levels and the presence of both immunoglobulin (Ig) M and IgG antibodies to human parvovirus B19 (HPV). A renal biopsy showed diffuse endocapillary proliferative glomerulonephritis. Immunofluorescence microscopy indicated 2+ granular staining for IgG, IgM, and C3 over the mesangial area and along glomerular capillary walls. HPV antigen was also detected in glomeruli by immunohistochemistry. Electron microscopy showed electron-dense deposits in the subendothelial space and the paramesangial area. These findings suggest that immune complex-type glomerulonephritis is caused by glomerular deposition of HPV antigen-antibody complexes in some patients with HPV infection.
  • |*Parvovirus B19, Human/immunology[MESH]
  • |Antigen-Antibody Complex[MESH]
  • |Antigens, Viral/analysis[MESH]
  • |Complement System Proteins/analysis[MESH]
  • |Erythema Infectiosum/*complications/immunology[MESH]
  • |Female[MESH]
  • |Glomerulonephritis/*complications/immunology/virology[MESH]
  • |Humans[MESH]
  • |Immunoglobulin G/analysis[MESH]
  • |Immunoglobulin M/analysis[MESH]
  • |Middle Aged[MESH]


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