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10.1016/s0166-3542(99)00048-0 http://scihub22266oqcxt.onion/10.1016/s0166-3542(99)00048-0 10669260!ä!10669260 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Antiviral+Res 1999 ; 44 (2): 103-11 Nephropedia Template TP {{tp|p=10669260|t=1999. Effect of Hochu-ekki-to (TJ-41), a Japanese herbal medicine, on the survival of mice infected with influenza virus |pdf=|usr=}}{{10669260}} gab.com Text Effect of Hochu-ekki-to (TJ-41), a Japanese herbal medicine, on the survival of mice infected with influenza virus JO: Antiviral Res http://www.kidney.de/pget.php?&tw=1&pmid=10669260 #FOAvip The antiviral effect of Hochu-ekki-to (TJ-41), a Japanese herbal medicine, was investigated using mice infected with influenza virus. TJ-41 was found to increase the survival rate, prolong the mean survival days, suppress viral growth in bronchoalveolar labage fluid (BALF) and inhibit the lung index (lung consolidation) on day 4 after infection in mice infected with influenza, after the agent had been administered orally once daily from day 7 to 2 before infection and from day 0 to 4 after infection. Administration of TJ-41 decreased the BALF concentrations of IL-1alpha, IL-6 and GM-CSF, but not TNF-alpha or interferon-gamma (IFN-gamma), on day 4 after infection. In addition, TJ-41 elevated the level of IFN-alpha in BALF on day 2 after infection. Yet, TJ-41 did not show any inhibitory effect on the growth of influenza virus in vitro. These results suggest that TJ-41 exerts its inhibitory effect on influenza virus infection via enhancement of the host immune responses in this experimental murine system. Twit Text FOAVip Effect of Hochu-ekki-to (TJ-41), a Japanese herbal medicine, on the survival of mice infected with influenza virus ????Antiviral Res http://www.kidney.de/pget.php?&tw=1&pmid=10669260 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=10669260 #FOAvip English Wikipedia <ref>{{Cite pmid|10669260}}</ref> Effect of Hochu-ekki-to (TJ-41), a Japanese herbal medicine, on the survival of mice infected with influenza virus #MMPMID10669260 Mori K; Kido T; Daikuhara H; Sakakibara I; Sakata T; Shimizu K; Amagaya S; Sasaki H; Komatsu Y Antiviral Res 1999[Dec]; 44 (2): 103-11 PMID10669260show ga The antiviral effect of Hochu-ekki-to (TJ-41), a Japanese herbal medicine, was investigated using mice infected with influenza virus. TJ-41 was found to increase the survival rate, prolong the mean survival days, suppress viral growth in bronchoalveolar labage fluid (BALF) and inhibit the lung index (lung consolidation) on day 4 after infection in mice infected with influenza, after the agent had been administered orally once daily from day 7 to 2 before infection and from day 0 to 4 after infection. Administration of TJ-41 decreased the BALF concentrations of IL-1alpha, IL-6 and GM-CSF, but not TNF-alpha or interferon-gamma (IFN-gamma), on day 4 after infection. In addition, TJ-41 elevated the level of IFN-alpha in BALF on day 2 after infection. Yet, TJ-41 did not show any inhibitory effect on the growth of influenza virus in vitro. These results suggest that TJ-41 exerts its inhibitory effect on influenza virus infection via enhancement of the host immune responses in this experimental murine system. |Administration, Oral[MESH] |Animals[MESH] |Antiviral Agents/chemistry/*pharmacology[MESH] |Bronchoalveolar Lavage Fluid/chemistry[MESH] |Chromatography, High Pressure Liquid[MESH] |Cytokines/*analysis[MESH] |Drugs, Chinese Herbal/administration & dosage/*pharmacology[MESH] |Enzyme-Linked Immunosorbent Assay[MESH] |Granulocyte-Macrophage Colony-Stimulating Factor/analysis[MESH] |Influenza A virus/*drug effects/immunology[MESH] |Interferon-gamma/analysis[MESH] |Interleukin-1/analysis[MESH] |Interleukin-6/analysis[MESH] |Male[MESH] |Mice[MESH] |Mice, Inbred BALB C[MESH] |Orthomyxoviridae Infections/*drug therapy/immunology/virology[MESH]Effect of Hochu-ekki-to (TJ-41), a Japanese herbal medicine, on the su(epmc).pdf DeepDyve Pubget Overpricing