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10.1007/s007050050010 http://scihub22266oqcxt.onion/10.1007/s007050050010 10664411!ä!10664411 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Arch+Virol 2000 ; 145 (1): 127-47 Nephropedia Template TP {{tp|p=10664411|t=2000. Neuron-glia interactions in the rat retina infected by Borna disease virus |pdf=|usr=}}{{10664411}} gab.com Text Neuron-glia interactions in the rat retina infected by Borna disease virus JO: Arch Virol http://www.kidney.de/pget.php?&tw=1&pmid=10664411 #FOAvip Neuron-glia interactions in the Borna disease virus (BDV)-infected rat retina were investigated with emphasis on the ultrastructural characterization of degenerative alterations in the ganglion cell and photoreceptor layer. Immuno- and cytochemical techniques were applied to label microglia, macrophages and Muller (macroglial) cells. Four weeks after intracerebral infection of adult rats, the total thickness of the retina was considerably diminished, primarily due to the loss of photoreceptor segments and ganglion cells. A gradual reduction of both plexiform layers was also observed. There was a remarkable increase in the number of microglial cells, predominantly in the ganglion cell and the inner plexiform layers. Ultrastructural analysis confirmed that microglia, but also macrophages, were involved in phagocytosis accompanying severe neuronal degeneration in the ganglion cell and the photoreceptor layer. In contrast, Muller cells showed moderate morphological and cytochemical alterations, indicating that Muller cells play only a minor role in early stages of BDV-induced retinitis. Monitoring neuron-glia interactions in BDV-induced retinopathy, combined with the application of different protocols of immunosuppression effecting the BDV virus and/or the microglia, might help to establish specific strategies to suppress BDV-induced neuronal degeneration. Twit Text FOAVip Neuron-glia interactions in the rat retina infected by Borna disease virus ????Arch Virol http://www.kidney.de/pget.php?&tw=1&pmid=10664411 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=10664411 #FOAvip English Wikipedia <ref>{{Cite pmid|10664411}}</ref> Neuron-glia interactions in the rat retina infected by Borna disease virus #MMPMID10664411 Kacza J; Vahlenkamp TW; Enbergs H; Richt JA; Germer A; Kuhrt H; Reichenbach A; Muller H; Herden C; Stahl T; Seeger J Arch Virol 2000[]; 145 (1): 127-47 PMID10664411show ga Neuron-glia interactions in the Borna disease virus (BDV)-infected rat retina were investigated with emphasis on the ultrastructural characterization of degenerative alterations in the ganglion cell and photoreceptor layer. Immuno- and cytochemical techniques were applied to label microglia, macrophages and Muller (macroglial) cells. Four weeks after intracerebral infection of adult rats, the total thickness of the retina was considerably diminished, primarily due to the loss of photoreceptor segments and ganglion cells. A gradual reduction of both plexiform layers was also observed. There was a remarkable increase in the number of microglial cells, predominantly in the ganglion cell and the inner plexiform layers. Ultrastructural analysis confirmed that microglia, but also macrophages, were involved in phagocytosis accompanying severe neuronal degeneration in the ganglion cell and the photoreceptor layer. In contrast, Muller cells showed moderate morphological and cytochemical alterations, indicating that Muller cells play only a minor role in early stages of BDV-induced retinitis. Monitoring neuron-glia interactions in BDV-induced retinopathy, combined with the application of different protocols of immunosuppression effecting the BDV virus and/or the microglia, might help to establish specific strategies to suppress BDV-induced neuronal degeneration. |Animals[MESH] |Borna Disease/*pathology/virology[MESH] |Borna disease virus/immunology/*isolation & purification[MESH] |Eye Infections, Viral/pathology/virology[MESH] |Immunohistochemistry[MESH] |Macrophages/immunology/pathology[MESH] |Microglia/pathology/ultrastructure[MESH] |Microscopy, Electron[MESH] |Nerve Degeneration[MESH] |Neuroglia/*pathology/physiology/ultrastructure[MESH] |Neurons/*pathology/physiology/ultrastructure[MESH] |Rats[MESH] |Rats, Inbred Lew[MESH] |Retina/*pathology/ultrastructure/virology[MESH] |Retinal Ganglion Cells/pathology[MESH] |Retinitis/*pathology/virology[MESH]Neuron-glia interactions in the rat retina infected by Borna disease v(epmc).pdf DeepDyve Pubget Overpricing