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Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 J+Neurovirol 1999 ; 5 (2): 196-9 Nephropedia Template TP
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Failure to demonstrate Borna disease virus genome in peripheral blood mononuclear cells from psychiatric patients in Korea #MMPMID10321984
Kim YK; Kim SH; Choi SH; Ko YH; Kim L; Lee MS; Suh KY; Kwak DI; Song KJ; Lee YJ; Yanagihara R; Song JW
J Neurovirol 1999[Apr]; 5 (2): 196-9 PMID10321984show ga
RNA, extracted from peripheral blood mononuclear cells (PBMC) obtained from 81 Korean psychiatric patients (39 with schizophrenia, 33 with bipolar affective disorders and nine with major depression), was analyzed for a 391-nucleotide, highly conserved region of the p24 protein-encoding ORF II of Borna disease virus (BDV), using nested reverse transcription-polymerase chain reaction (RT-PCR). BDV genomic RNA was not detected in PBMC from any of the 81 Korean psychiatric patients. These data do not support an etiologic association between BDV infection and neuropsychiatric disorders in humans.