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10.1080/2162402X.2015.1026532

http://scihub22266oqcxt.onion/10.1080/2162402X.2015.1026532
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suck abstract from ncbi


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pmid26504670
      Oncoimmunology 2015 ; 4 (11 ): e1026532
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  • ?3-adrenoreceptor and tumor microenvironment: a new hub #MMPMID26504670
  • Chiarugi P ; Filippi L
  • Oncoimmunology 2015[Nov]; 4 (11 ): e1026532 PMID26504670 show ga
  • The achievement of malignant traits in several cancers is associated with tumor microenvironment reactivity. New evidence show that the stress hormone noradrenaline enhances melanoma microenvironment reactivity, mainly acting through ?3-adrenoreceptors (?(2)-ARs), favoring recruitment of cancer-associated fibroblasts, M2-macrophages, bone marrow-derived precursors, These events concur in sustaining a pro-inflammatory and pro-angiogenic milieu, finally boosting melanoma malignancy.
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