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10.1016/B978-0-12-394440-5.00014-0

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suck abstract from ncbi


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pmid23764061
      Prog+Mol+Biol+Transl+Sci 2013 ; 118 (ä): 359-93
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  • ?-Arrestins in the immune system #MMPMID23764061
  • Jiang D ; Xie T ; Liang J ; Noble PW
  • Prog Mol Biol Transl Sci 2013[]; 118 (ä): 359-93 PMID23764061 show ga
  • ?-Arrestins regulate G protein-coupled receptors through receptor desensitization while also acting as signaling scaffolds to facilitate numerous effector pathways. Recent studies have provided evidence that ?-arrestins play a key role in inflammatory responses. Here, we summarize these advances on the roles of ?-arrestins in immune regulation and inflammatory responses under physiological and pathological conditions, with an emphasis on translational implications of ?-arrestins on human diseases.
  • |Adaptive Immunity [MESH]
  • |Animals [MESH]
  • |Arrestins/*metabolism [MESH]
  • |Humans [MESH]
  • |Immune System/*metabolism [MESH]
  • |Immunity, Innate [MESH]
  • |Inflammation/drug therapy/metabolism [MESH]
  • |Signal Transduction/immunology [MESH]


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