Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.1111/acer.12568 http://scihub22266oqcxt.onion/10.1111/acer.12568 C4293208!4293208 !25406797     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25406797 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Alcohol+Clin+Exp+Res 2014 ; 38 (12 ): 2925-33 Nephropedia Template TP {{tp|p=25406797 |t=2014. Widespread effects of alcohol on white matter microstructure |pdf=|usr=}}{{25406797 }} gab.com Text Widespread effects of alcohol on white matter microstructure JO: Alcohol Clin Exp Res http://www.kidney.de/pget.php?&tw=1&pmid=25406797 #FOAvip BACKGROUND: Evidence suggests that chronic misuse of alcohol may preferentially affect the integrity of frontal white matter (WM) tracts, which can impact executive functions important to achieve and maintain abstinence. METHODS: Global and regional WM microstructure was assessed using diffusion magnetic resonance measures of fractional anisotropy (FA) for 31 abstinent alcoholics (ALC) with an average of 25 years of abuse and approximately 5 years of sobriety and 20 nonalcoholic control (NC) participants. Data processing was conducted with FreeSurfer and FSL processing streams. Voxelwise processing of the FA data was carried out using tract-based spatial statistics. Clusters of significance were created to provide a quantitative summary of highly significant regions within the voxelwise analysis. RESULTS: Widespread, bilateral reductions in FA were observed in ALC as compared to NC participants in multiple frontal, temporal, parietal, and cerebellar WM tracts. FA in the left inferior frontal gyrus was associated with drinking severity. CONCLUSIONS: This study found widespread reductions in WM integrity in a group of ALC compared to NC participants, with most pronounced effects in frontal and superior tracts. Decreased FA throughout the frontostriatal circuits that mediate inhibitory control may result in impulsive behavior and inability to maintain sobriety. Twit Text FOAVip Widespread effects of alcohol on white matter microstructure ????Alcohol Clin Exp Res http://www.kidney.de/pget.php?&tw=1&pmid=25406797 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25406797 #FOAvip English Wikipedia <ref>{{Cite pmid|25406797 }}</ref> Widespread effects of alcohol on white matter microstructure #MMPMID25406797 Fortier CB ; Leritz EC ; Salat DH ; Lindemer E ; Maksimovskiy AL ; Shepel J ; Williams V ; Venne JR ; Milberg WP ; McGlinchey RE Alcohol Clin Exp Res 2014[Dec]; 38 (12 ): 2925-33 PMID25406797 show ga BACKGROUND: Evidence suggests that chronic misuse of alcohol may preferentially affect the integrity of frontal white matter (WM) tracts, which can impact executive functions important to achieve and maintain abstinence. METHODS: Global and regional WM microstructure was assessed using diffusion magnetic resonance measures of fractional anisotropy (FA) for 31 abstinent alcoholics (ALC) with an average of 25 years of abuse and approximately 5 years of sobriety and 20 nonalcoholic control (NC) participants. Data processing was conducted with FreeSurfer and FSL processing streams. Voxelwise processing of the FA data was carried out using tract-based spatial statistics. Clusters of significance were created to provide a quantitative summary of highly significant regions within the voxelwise analysis. RESULTS: Widespread, bilateral reductions in FA were observed in ALC as compared to NC participants in multiple frontal, temporal, parietal, and cerebellar WM tracts. FA in the left inferior frontal gyrus was associated with drinking severity. CONCLUSIONS: This study found widespread reductions in WM integrity in a group of ALC compared to NC participants, with most pronounced effects in frontal and superior tracts. Decreased FA throughout the frontostriatal circuits that mediate inhibitory control may result in impulsive behavior and inability to maintain sobriety. |*Alcohol Abstinence/psychology [MESH] |Adult [MESH] |Alcoholism/*metabolism/*pathology/psychology [MESH] |Cross-Sectional Studies [MESH] |Diffusion Tensor Imaging/methods [MESH] |Executive Function/physiology [MESH] |Female [MESH] |Humans [MESH] |Male [MESH] |Middle Aged [MESH] |Neuropsychological Tests [MESH]Widespread effects of alcohol on white matter microstructure (epmc).pdf DeepDyve Pubget Overpricing