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2017 ; 9
(2
): 65-69
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Wells Syndrome Successfully Treated with Colchicine
#MMPMID28868003
Puzas ÁI
; Álvarez LM
; Menéndez ÁF
; Romero Yuste S
; Gómez OP
Case Rep Dermatol
2017[May]; 9
(2
): 65-69
PMID28868003
show ga
Eosinophilic cellulitis is an uncommon, inflammatory and chronic disorder of
unknown etiology. Corticosteroids are currently considered as the first-line
treatment but they are not without significant disadvantages such as
contraindications in steroid-resistant cases and patients with frequent
recurrences. We report a patient suffering from Wells' syndrome with a 24-year
history of symptomatic and generalized skin lesions. After consultation in our
department, treatment with colchicine 1 mg/day was prescribed resulting in large
clinical improvement. No side effects have been recorded. To our knowledge, this
is an original disease approach. Although small, our clinical experience supports
the inclusion of colchicine in the drug armamentarium when treating patients
suffering from Wells' syndrome. Indeed, its excellent safety profile makes it
very attractive for patients with frequent recurrent episodes who need secure
options for the medium- and long-term disease control.