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10.3389/fmolb.2017.00072

http://scihub22266oqcxt.onion/10.3389/fmolb.2017.00072
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C5694535!5694535 !29184887
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pmid29184887
      Front+Mol+Biosci 2017 ; 4 (ä): 72
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  • Weak Molecular Interactions in Clathrin-Mediated Endocytosis #MMPMID29184887
  • Smith SM ; Baker M ; Halebian M ; Smith CJ
  • Front Mol Biosci 2017[]; 4 (ä): 72 PMID29184887 show ga
  • Clathrin-mediated endocytosis is a process by which specific molecules are internalized from the cell periphery for delivery to early endosomes. The key stages in this step-wise process, from the starting point of cargo recognition, to the later stage of assembly of the clathrin coat, are dependent on weak interactions between a large network of proteins. This review discusses the structural and functional data that have improved our knowledge and understanding of the main weak molecular interactions implicated in clathrin-mediated endocytosis, with a particular focus on the two key proteins: AP2 and clathrin.
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