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10.1208/s12248-014-9705-5 http://scihub22266oqcxt.onion/10.1208/s12248-014-9705-5 C4365088!4365088!25466495     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25466495.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       AAPS+J 2015 ; 17 (2): 313-22 Nephropedia Template TP {{tp|p=25466495|t=2015. Vitamin E Transporters in Cancer Therapy |pdf=|usr=}}{{25466495}} gab.com Text Vitamin E Transporters in Cancer Therapy JO: AAPS J http://www.kidney.de/pget.php?&tw=1&pmid=25466495 #FOAvip Besides their potent antioxidant activity, vitamin E isoforms demonstrated multiple therapeutic activities among which is their activity against different cancer types, including breast, prostate, and colon cancers. However, the activity of vitamin E isoforms is limited by their low bioavailability following oral administration. In addition to the low solubility, vitamin E isoforms have been established as substrates for several intestinal and hepatic transport proteins. In this review, we present reported anticancer activity of vitamin E family members and the possible utilization of vitamin E and derivatives as chemosensitizers to reverse multidrug resistance when given as part of a delivery system and/or in combination with anticancer therapeutic drugs. Then, the review discusses disposition of vitamin E members and transport proteins that play a role in determining their systemic bioavailability followed by recent advances in vitamin E formulations and delivery strategies. Twit Text FOAVip Vitamin E Transporters in Cancer Therapy ????AAPS J http://www.kidney.de/pget.php?&tw=1&pmid=25466495 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=25466495 #FOAvip English Wikipedia <ref>{{Cite pmid|25466495}}</ref> Vitamin E Transporters in Cancer Therapy #MMPMID25466495 Alqahtani S; Kaddoumi A AAPS J 2015[Mar]; 17 (2): 313-22 PMID25466495show ga Besides their potent antioxidant activity, vitamin E isoforms demonstrated multiple therapeutic activities among which is their activity against different cancer types, including breast, prostate, and colon cancers. However, the activity of vitamin E isoforms is limited by their low bioavailability following oral administration. In addition to the low solubility, vitamin E isoforms have been established as substrates for several intestinal and hepatic transport proteins. In this review, we present reported anticancer activity of vitamin E family members and the possible utilization of vitamin E and derivatives as chemosensitizers to reverse multidrug resistance when given as part of a delivery system and/or in combination with anticancer therapeutic drugs. Then, the review discusses disposition of vitamin E members and transport proteins that play a role in determining their systemic bioavailability followed by recent advances in vitamin E formulations and delivery strategies. äVitamin E Transporters in Cancer Therapy (epmc).pdf DeepDyve Pubget Overpricing