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2014 ; 89
(3
): 472-7
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Variants of dermatofibroma--a histopathological study
#MMPMID24937822
Alves JV
; Matos DM
; Barreiros HF
; Bártolo EA
An Bras Dermatol
2014[May]; 89
(3
): 472-7
PMID24937822
show ga
Several variants of dermatofibroma have been described. They are essentially
distinguished by their clinical and histopathological features. To review the
mainfeaturesof these variants, a retrospective study of skin biopsies and tissue
excisions of dermatofibromasperformed in the dermatology and venereology service
at the Hospital Garcia de Orta between May 2007 and April 2012 was carried out.
During that period, 192 dermatofibromas were diagnosed in 181 patients, the
lesions being more common in women. Median age of the study population was 48
years. The most common lesion site was the limbs (74% of patients). The
histopathological types found were common fibrous histiocytoma (80%) and the
aneurysmal (5.7%),hemosiderotic (5.7%), epithelioid (2.6%), cellular (2.1%),
lipidized (2.1%), atrophic (1.0) and clear cell (0.5%) variants. Based on these
findings, this review focuses on the clinical and histological features of the
various variants of dermatofibroma in terms of their clinical presentation,
distinct histopathological features, differential diagnosis and prognosis.
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