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10.4161/hv.28428 http://scihub22266oqcxt.onion/10.4161/hv.28428 C5396221!5396221 !24637887     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=24637887 &cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\24637887 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Hum+Vaccin+Immunother 2014 ; 10 (6 ): 1466-77 Nephropedia Template TP {{tp|p=24637887 |t=2014. Vaccines against Clostridium difficile |pdf=|usr=}}{{24637887 }} gab.com Text Vaccines against Clostridium difficile JO: Hum Vaccin Immunother http://www.kidney.de/pget.php?&tw=1&pmid=24637887 #FOAvip Clostridium difficile infection (CDI) is recognized as a major cause of nosocomial diseases ranging from antibiotic related diarrhea to fulminant colitis. Emergence during the last 2 decades of C. difficile strains associated with high incidence, severity and lethal outcomes has increased the challenges for CDI treatment. A limited number of drugs have proven to be effective against CDI and concerns about antibiotic resistance as well as recurring disease solicited the search for novel therapeutic strategies. Active vaccination provides the attractive opportunity to prevent CDI, and intense research in recent years led to development of experimental vaccines, 3 of which are currently under clinical evaluation. This review summarizes recent achievements and remaining challenges in the field of C. difficile vaccines, and discusses future perspectives in view of newly-identified candidate antigens. Twit Text FOAVip Vaccines against Clostridium difficile ????Hum Vaccin Immunother http://www.kidney.de/pget.php?&tw=1&pmid=24637887 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24637887 #FOAvip English Wikipedia <ref>{{Cite pmid|24637887 }}</ref> Vaccines against Clostridium difficile #MMPMID24637887 Leuzzi R ; Adamo R ; Scarselli M Hum Vaccin Immunother 2014[]; 10 (6 ): 1466-77 PMID24637887 show ga Clostridium difficile infection (CDI) is recognized as a major cause of nosocomial diseases ranging from antibiotic related diarrhea to fulminant colitis. Emergence during the last 2 decades of C. difficile strains associated with high incidence, severity and lethal outcomes has increased the challenges for CDI treatment. A limited number of drugs have proven to be effective against CDI and concerns about antibiotic resistance as well as recurring disease solicited the search for novel therapeutic strategies. Active vaccination provides the attractive opportunity to prevent CDI, and intense research in recent years led to development of experimental vaccines, 3 of which are currently under clinical evaluation. This review summarizes recent achievements and remaining challenges in the field of C. difficile vaccines, and discusses future perspectives in view of newly-identified candidate antigens. |Anti-Bacterial Agents/*adverse effects [MESH] |Bacterial Vaccines/*immunology/*isolation & purification [MESH] |Clinical Trials as Topic [MESH] |Clostridioides difficile/*immunology [MESH] |Clostridium Infections/immunology/*prevention & control [MESH] |Cross Infection/chemically induced/prevention & control [MESH] |Diarrhea/*chemically induced/*prevention & control [MESH] |Drug Discovery/trends [MESH]Vaccines against Clostridium difficile (epmc).pdf DeepDyve Pubget Overpricing