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2016 ; 14
(3
): e1002417
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Using Sex to Cure the Genome
#MMPMID26987049
Rocha EP
PLoS Biol
2016[Mar]; 14
(3
): e1002417
PMID26987049
show ga
The diversification of prokaryotes is accelerated by their ability to acquire DNA
from other genomes. However, the underlying processes also facilitate genome
infection by costly mobile genetic elements. The discovery that cells can uptake
DNA by natural transformation was instrumental to the birth of molecular biology
nearly a century ago. Surprisingly, a new study shows that this mechanism could
efficiently cure the genome of mobile elements acquired through previous sexual
exchanges.