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Toubes ME
; Lama A
; Ferreiro L
; Golpe A
; Álvarez-Dobaño JM
; González-Barcala FJ
; San José E
; Rodríguez-Núñez N
; Rábade C
; Lourido T
; Valdés L
J Thorac Dis
2017[May]; 9
(5
): 1209-1218
PMID28616270
show ga
BACKGROUND: The characteristics of patients with urinothorax (UT) are poorly
defined. METHODS: A systematic review was performed searching for studies
reporting clinical findings, pleural fluid (PF) characteristics, and the most
effective treatment of UT. Case descriptions and retrospective studies were
included. RESULTS: The review included 78 studies with a total of 88 patients.
Median age was 45 years, male/female ratio was 1.6:1 and in 76% of cases the
etiology was trauma. Pleural effusion (PE) was predominantly unilateral (87%) and
occupied over 2/3 of the hemithorax in most cases (64.4%). PF was straw-colored
(72.7%) or hematic (27.3%) with urine-like odor in all cases. PF was transudate
in 56.2% of cases (18/32) and among 14 exudates (43.8%), 3 were concordant
exudates, 1 protein-discordant and 10 LDH-discordant, with lymphocyte (44.4%) and
neutrophil (38.5%) predominance. The PF/serum (PF/S) creatinine ratio was >1 in
all cases except one (97.9%). The diagnosis was established on the basis of PF/S
creatinine ratio >1 (56.6%), urinary tract contrast extravasation (12%), abnormal
computed tomography (8.4%), laparotomy findings (6%), and association of
obstructive uropathy with PE (6%). The outcome was favorable (74/77; 96.1%) when
treatment was direct towards the uropathy (alone or associated with
thoracentesis/thoracic drainage). Outcome was unfavorable in the 15 patients who
were only treated with thoracentesis/thoracic drainage. CONCLUSIONS: UT is
usually traumatic, unilateral, and PF does not have a specific pattern or
cellularity predominance, with a PF/S creatinine ratio almost always >1.
Treatment should include the uropathy, with or without PF evacuation.