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2014 ; 9
(5
): 425-430
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Update on the prevention and treatment of endophthalmitis
#MMPMID26609317
Schwartz SG
; Flynn HW Jr
Expert Rev Ophthalmol
2014[Oct]; 9
(5
): 425-430
PMID26609317
show ga
Endophthalmitis remains a rare but serious cause of visual loss. Over time,
changes have been noted in endophthalmitis in terms of predominant causes,
infecting organisms, and antibiotic susceptibilities. There is controversy
regarding the use of intracameral prophylactic antimicrobials during cataract
surgery. Alternatively, there appears to be increasing evidence against using
routine topical antibiotics for intravitreal injections. There are also
increasing reports of multidrug-resistant organisms causing endophthalmitis, but
the combination of vancomycin and ceftazidime appears effective for the vast
majority of cases. Future trends may involve increasing utilization of polymerase
chain reaction for diagnosis, and possibly office-based pars plana vitrectomy for
treatment of endophthalmitis.