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2015 ; 6
(Suppl 1
): S282-4
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Unusual presentation of oral amyloidosis
#MMPMID26604589
Contemp Clin Dent
2015[Sep]; 6
(Suppl 1
): S282-4
PMID26604589
show ga
Amyloidosis is a rare disease of difficult diagnosis that occurs due accumulation
of amyloid substance localized or systemic. The oral cavity is an unusual site
and can be related to both localized and systemic forms and for that reason a
full investigation is necessary to determine the extent of the disease. This
study reports a case of a 58-year-old melanoderm male patient referred to the
Department of Oral and Maxillofacial Surgery with white plaques on the tongue and
multiple nodules in the region of the buccal mucosa and labial commissure, with 6
months of evolution and painful symptoms. An incisional biopsy was performed on
both sites and histological examination indicated the presence of eosinophilic
amorphous material within the connective tissue, positive for crystal violet
staining, consistent with amyloidosis. At the present time, there is no consensus
on the management of local amyloidosis. Surgical treatment of localized forms is
indicated in some cases to reduce the functional prejudice. Moreover, follow-up
is mandatory, both to manage recurrences and to monitor the possible evolution of
the disease to the systemic form.