Unruptured Cerebral Aneurysms: Evaluation and Management
#MMPMID26146657
Ajiboye N
; Chalouhi N
; Starke RM
; Zanaty M
; Bell R
ScientificWorldJournal
2015[]; 2015
(?): 954954
PMID26146657
show ga
The evolution of imaging techniques and their increased use in clinical practice
have led to a higher detection rate of unruptured intracranial aneurysms. The
diagnosis of an unruptured intracranial aneurysm is a source of significant
stress to the patient because of the concerns for aneurysmal rupture, which is
associated with substantial rates of morbidity and mortality. Therefore, it is
important that decisions regarding optimum management are made based on the
comparison of the risk of aneurysmal rupture with the risk associated with
intervention. This review provides a comprehensive overview of the epidemiology,
pathophysiology, natural history, clinical presentation, diagnosis, and
management options for unruptured intracranial aneurysms based on the current
evidence in the literature. Furthermore, the authors discuss the genetic
abnormalities associated with intracranial aneurysm and current guidelines for
screening in patients with a family history of intracranial aneurysms. Since
there is significant controversy in the optimum management of small unruptured
intracranial aneurysms, we provided a systematic approach to their management
based on patient and aneurysm characteristics as well as the risks and benefits
of intervention.
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