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10.1038/ejhg.2014.36 http://scihub22266oqcxt.onion/10.1038/ejhg.2014.36 C4231405!4231405 !24667789     free     free     free Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\24667789 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Eur+J+Hum+Genet 2014 ; 22 (12 ): 1404-12 Nephropedia Template TP {{tp|p=24667789 |t=2014. Unravelling the distinct strains of Tharu ancestry |pdf=|usr=}}{{24667789 }} gab.com Text Unravelling the distinct strains of Tharu ancestry JO: Eur J Hum Genet http://www.kidney.de/pget.php?&tw=1&pmid=24667789 #FOAvip The northern region of the Indian subcontinent is a vast landscape interlaced by diverse ecologies, for example, the Gangetic Plain and the Himalayas. A great number of ethnic groups are found there, displaying a multitude of languages and cultures. The Tharu is one of the largest and most linguistically diverse of such groups, scattered across the Tarai region of Nepal and bordering Indian states. Their origins are uncertain. Hypotheses have been advanced postulating shared ancestry with Austroasiatic, or Tibeto-Burman-speaking populations as well as aboriginal roots in the Tarai. Several Tharu groups speak a variety of Indo-Aryan languages, but have traditionally been described by ethnographers as representing East Asian phenotype. Their ancestry and intra-population diversity has previously been tested only for haploid (mitochondrial DNA and Y-chromosome) markers in a small portion of the population. This study presents the first systematic genetic survey of the Tharu from both Nepal and two Indian states of Uttarakhand and Uttar Pradesh, using genome-wide SNPs and haploid markers. We show that the Tharu have dual genetic ancestry as up to one-half of their gene pool is of East Asian origin. Within the South Asian proportion of the Tharu genetic ancestry, we see vestiges of their common origin in the north of the South Asian Subcontinent manifested by mitochondrial DNA haplogroup M43. Twit Text FOAVip Unravelling the distinct strains of Tharu ancestry ????Eur J Hum Genet http://www.kidney.de/pget.php?&tw=1&pmid=24667789 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=24667789 #FOAvip English Wikipedia <ref>{{Cite pmid|24667789 }}</ref> Unravelling the distinct strains of Tharu ancestry #MMPMID24667789 Chaubey G ; Singh M ; Crivellaro F ; Tamang R ; Nandan A ; Singh K ; Sharma VK ; Pathak AK ; Shah AM ; Sharma V ; Singh VK ; Selvi Rani D ; Rai N ; Kushniarevich A ; Ilumäe AM ; Karmin M ; Phillip A ; Verma A ; Prank E ; Singh VK ; Li B ; Govindaraj P ; Chaubey AK ; Dubey PK ; Reddy AG ; Premkumar K ; Vishnupriya S ; Pande V ; Parik J ; Rootsi S ; Endicott P ; Metspalu M ; Lahr MM ; van Driem G ; Villems R ; Kivisild T ; Singh L ; Thangaraj K Eur J Hum Genet 2014[Dec]; 22 (12 ): 1404-12 PMID24667789 show ga The northern region of the Indian subcontinent is a vast landscape interlaced by diverse ecologies, for example, the Gangetic Plain and the Himalayas. A great number of ethnic groups are found there, displaying a multitude of languages and cultures. The Tharu is one of the largest and most linguistically diverse of such groups, scattered across the Tarai region of Nepal and bordering Indian states. Their origins are uncertain. Hypotheses have been advanced postulating shared ancestry with Austroasiatic, or Tibeto-Burman-speaking populations as well as aboriginal roots in the Tarai. Several Tharu groups speak a variety of Indo-Aryan languages, but have traditionally been described by ethnographers as representing East Asian phenotype. Their ancestry and intra-population diversity has previously been tested only for haploid (mitochondrial DNA and Y-chromosome) markers in a small portion of the population. This study presents the first systematic genetic survey of the Tharu from both Nepal and two Indian states of Uttarakhand and Uttar Pradesh, using genome-wide SNPs and haploid markers. We show that the Tharu have dual genetic ancestry as up to one-half of their gene pool is of East Asian origin. Within the South Asian proportion of the Tharu genetic ancestry, we see vestiges of their common origin in the north of the South Asian Subcontinent manifested by mitochondrial DNA haplogroup M43. |Asian People/*genetics [MESH] |Chromosomes, Human, Y/genetics [MESH] |DNA, Mitochondrial/genetics [MESH] |Ethnicity/*genetics [MESH] |Genetic Association Studies [MESH] |Genetic Variation [MESH] |Genotyping Techniques [MESH] |Haplotypes [MESH] |Humans [MESH] |India [MESH] |Nepal [MESH] |Phylogeography [MESH] |Polymorphism, Single Nucleotide [MESH]Unravelling the distinct strains of Tharu ancestry (epmc).pdf DeepDyve Pubget Overpricing