Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\25950760
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Int+J+Mol+Sci
2015 ; 16
(5
): 10121-33
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Ultrasound tissue characterization of vulnerable atherosclerotic plaque
#MMPMID25950760
Picano E
; Paterni M
Int J Mol Sci
2015[May]; 16
(5
): 10121-33
PMID25950760
show ga
A thrombotic occlusion of the vessel fed by ruptured coronary atherosclerotic
plaque may result in unstable angina, myocardial infarction or death, whereas
embolization from a plaque in carotid arteries may result in transient ischemic
attack or stroke. The atherosclerotic plaque prone to such clinical events is
termed high-risk or vulnerable plaque, and its identification in humans before it
becomes symptomatic has been elusive to date. Ultrasonic tissue characterization
of the atherosclerotic plaque is possible with different techniques--such as
vascular, transesophageal, and intravascular ultrasound--on a variety of arterial
segments, including carotid, aorta, and coronary districts. The image analysis
can be based on visual, video-densitometric or radiofrequency methods and
identifies three distinct textural patterns: hypo-echoic (corresponding to lipid-
and hemorrhage-rich plaque), iso- or moderately hyper-echoic (fibrotic or
fibro-fatty plaque), and markedly hyperechoic with shadowing (calcific plaque).
Hypoechoic or dishomogeneous plaques, with spotty microcalcification and large
plaque burden, with plaque neovascularization and surface irregularities by
contrast-enhanced ultrasound, are more prone to clinical complications than
hyperechoic, extensively calcified, homogeneous plaques with limited plaque
burden, smooth luminal plaque surface and absence of neovascularization. Plaque
ultrasound morphology is important, along with plaque geometry, in determining
the atherosclerotic prognostic burden in the individual patient. New quantitative
methods beyond backscatter (to include speed of sound, attenuation, strain,
temperature, and high order statistics) are under development to evaluate
vascular tissues. Although not yet ready for widespread clinical use, tissue
characterization is listed by the American Society of Echocardiography roadmap to
2020 as one of the most promising fields of application in cardiovascular
ultrasound imaging, offering unique opportunities for the early detection and
treatment of atherosclerotic disease.
free
free
free
